S
Shin ichiro Takai
Researcher at Osaka University
Publications - 12
Citations - 1281
Shin ichiro Takai is an academic researcher from Osaka University. The author has contributed to research in topics: Locus (genetics) & Genetic linkage. The author has an hindex of 7, co-authored 12 publications receiving 1262 citations.
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Journal ArticleDOI
The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis.
Charis Eng,Charis Eng,David Clayton,I Schuffenecker,Gilbert M. Lenoir,Gilbert J. Cote,Robert F. Gagel,Hans Kristian Ploos van Amstel,Cornelis J.M. Lips,Isamu Nishisho,Shin ichiro Takai,Deborah J. Marsh,Deborah J. Marsh,Bruce G. Robinson,Karin Frank-Raue,Friedhelm Raue,Feiyu Xue,Walter W. Noll,Cristina Romei,Furio Pacini,Monika Fink,Bruno Niederle,Jan Zedenius,Magnus Nordenskjöld,Paul Komminoth,Geoffrey N. Hendy,Hossein Gharib,Stephen N. Thibodeau,André Lacroix,Andrea Frilling,Bruce A.J. Ponder,Bruce A.J. Ponder,Lois M. Mulligan +32 more
TL;DR: It is suggested that genotype-phenotype correlations do exist and, if made reliably absolute, could prove useful in the future in clinical management with respect to screening, surveillance, and prophylaxis, as well as provide insight into the genetic effects of particular mutations.
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Comparison of FDG-PET with MIBI-SPECT in the detection of breast cancer and axillary lymph node metastasis.
Kenji Yutani,Eiichi Shiba,Hideo Kusuoka,Mitsuaki Tatsumi,Toshiisa Uehara,Tetsuya Taguchi,Shin ichiro Takai,Tsunehiko Nishimura +7 more
TL;DR: Neither FDG-PET nor MIBI-SPECT is sufficiently sensitive to rule out axillary lymph node metastasis in the detection of breast cancer and axillaryymph node metastase in the same patients, indicating that MIBI's SPECT is comparable with FDg-PET in detecting breast cancer.
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Loss of genes on chromosome 22 in medullary thyroid carcinoma and pheochromocytoma.
Shin ichiro Takai,Hideo Tateishi,Isamu Nishisho,Tetsuro Miki,Kazuyoshi Motomura,Akira Miyauchi,Makoto Kato,Tatsuro Ikeuchi,Kohtaro Yamamoto,Makoto Okazaki,Masayuki Yamamoto,Tasuku Honjo,Yuichi Kumahara,Takesada Mori +13 more
TL;DR: The results suggest that loss or mutation of a gene on chromosome 22 may play an important role in tumorigenesis in MEN2A.
Journal ArticleDOI
Isolation and mapping of cosmid markers on human chromosome 22, including one within the submicroscopically deleted region of DiGeorge syndrome.
Hiroki Kurahashi,Kenzo Akagi,Katsu Karakawa,Tsutomu Nakamura,Jan P. Dumanski,Tetsuya Sano,Shintaro Okada,Shin ichiro Takai,Isamu Nishisho +8 more
TL;DR: A genomic cosmid library was constructed from a Chinese hamster/human hybrid cell containing human intact chromosome 22 as its only human component and 108 cosmids regionally assigned to human chromosome 22 should be useful for the construction of long-range physical maps and the identification of genetic alterations on the chromosome.
Journal ArticleDOI
Evaluation of surgical results and prediction of prognosis in patients with medullary thyroid carcinoma by analysis of serum calcitonin levels.
Akira Miyauchi,Fumio Matsuzuka,Kanji Kuma,Shin ichiro Takai,Kembu Nakamoto,Kenji Nakamura,Satoru Nanjo,Masazumi Maeda +7 more
TL;DR: These parameters allow quantitative judgment of the effect of surgery and quantitative prediction of the prognosis in each patient, and the expected duration of survival after surgery.