Shinichi Hosokawa

TL;DR: It is shown that Sox9 is expressed throughout the biliary and pancreatic ductal epithelia, which are connected to the intestinal stem-cell zone, which suggests interdependence between the structure and homeostasis of endodermal organs, with Sox9 expression being linked to progenitor status.

TL;DR: 99mTc dimercaptosuccinic acid is a new renal scanning agent that provides a good quality of renal image as a result of preferential cortical accumulation and also makes feasible a quantitative assessment of separate kidney function, correlating well with renal plasma flow obtained from a 131I hippuran renogram of each kidney.

TL;DR: Serum Al and Si levels in the HD patients with peripheral neurological disorder (excluding encephalopathy) and with bone disease were significantly high, and were negatively correlated with indicators of anemia such as RBC, hemoglobin and hematocrit values.

TL;DR: 99mTc-DMSA scintigraphy has advantages over conventional methods in that it can be performed repeatedly with little discomfort to the patients, as a routine clinical examination, suggesting that DMSA should be termed a cortical tubular marker.

TL;DR: It is suggested that Hes1-mediated Notch activity determines the plasticity of adult pancreatic duct cells and that there may exist a dosage requirement of Sox9 for keeping the duct cell identity in the adult pancreas.