T
Toshihiko Masui
Researcher at Kyoto University
Publications - 133
Citations - 3463
Toshihiko Masui is an academic researcher from Kyoto University. The author has contributed to research in topics: Pancreatic cancer & Medicine. The author has an hindex of 24, co-authored 105 publications receiving 2967 citations.
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Journal ArticleDOI
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
Kenichiro Furuyama,Yoshiya Kawaguchi,Haruhiko Akiyama,Masashi Horiguchi,S. Kodama,T. Kuhara,Shinichi Hosokawa,Ashraf Elbahrawy,Tsunemitsu Soeda,Masayuki Koizumi,Toshihiko Masui,Michiya Kawaguchi,Kyoichi Takaori,Ryuichiro Doi,Eiichiro Nishi,Ryosuke Kakinoki,Jian Min Deng,Richard R. Behringer,Takashi Nakamura,Shinji Uemoto +19 more
TL;DR: It is shown that Sox9 is expressed throughout the biliary and pancreatic ductal epithelia, which are connected to the intestinal stem-cell zone, which suggests interdependence between the structure and homeostasis of endodermal organs, with Sox9 expression being linked to progenitor status.
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A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer
Masashi Kanai,Kenichi Yoshimura,Masanori Asada,Atsushi Imaizumi,Chihiro Suzuki,Shigemi Matsumoto,Takafumi Nishimura,Yukiko Mori,Toshihiko Masui,Yoshiya Kawaguchi,Kazuhiro Yanagihara,Shujiro Yazumi,Tsutomu Chiba,Sushovan Guha,Bharat B. Aggarwal +14 more
TL;DR: Combination therapy using 8 g oral curcumin daily with gemcitabine-based chemotherapy was safe and feasible in patients with pancreatic cancer and warrants further investigation into its efficacy.
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Impact of preoperative quality as well as quantity of skeletal muscle on survival after resection of pancreatic cancer.
Shinya Okumura,Toshimi Kaido,Yuhei Hamaguchi,Yasuhiro Fujimoto,Toshihiko Masui,Masaki Mizumoto,Ahmed Hammad,Akira Mori,Kyoichi Takaori,Shinji Uemoto +9 more
TL;DR: Preoperative sarcopenia, indicating low quality and quantity of skeletal muscle, is closely related to mortality after resection of pancreatic cancer.
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Metastin and its variant forms suppress migration of pancreatic cancer cells
Toshihiko Masui,Ryuichiro Doi,Tomohiko Mori,Eiji Toyoda,Masayuki Koizumi,Kazuhiro Kami,Daisuke Ito,Stephen C. Peiper,James R. Broach,Shinya Oishi,Ayumu Niida,Nobutaka Fujii,Masayuki Imamura +12 more
TL;DR: The data suggest that the metastin receptor, hOT7T175, is one of the promising targets for suppression of metastasis, and that small metastin variants could be an anti-metastatic agent to pancreatic cancer.
Journal ArticleDOI
Expression of integrin alphaVbeta3 in pancreatic carcinoma: relation to MMP-2 activation and lymph node metastasis.
Ryo Hosotani,Michiya Kawaguchi,Toshihiko Masui,Takatomo Koshiba,Jyun Ida,Koji Fujimoto,Michihiko Wada,Ryuichiro Doi,Masayuki Imamura +8 more
TL;DR: Examining expression analysis in pancreatic cancer tissue demonstrated involvement of alphaVbeta3 integrin in lymph node metastasis rather than peripancreatic invasion, and MMP-2 activation is linked, at least in part, to the expression of integrin alphaV beta3 of pancreaticcancer cells.