S
Shln Ichl Nagai
Researcher at National Institute for Basic Biology, Japan
Publications - 1
Citations - 632
Shln Ichl Nagai is an academic researcher from National Institute for Basic Biology, Japan. The author has contributed to research in topics: Enhancer & Mitogen-activated protein kinase. The author has an hindex of 1, co-authored 1 publications receiving 619 citations.
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The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
Tohru Ishitani,Jun Ninomiya-Tsuji,Shln Ichl Nagai,Michiru Nishita,Marc D. Meneghini,Nick Barker,Marian L. Waterman,Bruce Bowerman,Hans Clevers,Hiroshi Shibuya,Kunihiro Matsumoto +10 more
TL;DR: It is shown that TAK1 activation stimulates NLK activity and downregulates transcriptional activation mediated by β-catenin and TCF, which negatively regulates the Wnt signalling pathway.