Institution
Anhui University
Education•Hefei, Anhui, China•
About: Anhui University is a education organization based out in Hefei, Anhui, China. It is known for research contribution in the topics: Computer science & Catalysis. The organization has 17286 authors who have published 16777 publications receiving 210550 citations. The organization is also known as: ānhuī dàxué.
Papers published on a yearly basis
Papers
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TL;DR: The crystal structure of the C-terminal domain of SARS-CoV-2 (SARS- coV- 2-CTD) spike (S) protein in complex with human ACE2 (hACE2) is presented, which reveals a hACE2-binding mode similar overall to that observed for SARS -CoV.
2,334 citations
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TL;DR: Two monoclonal antibodies isolated from a patient with COVID-19 are shown to interfere with SARS-CoV-2–receptor binding, and one displays potent action against this virus in vitro and in a rhesus macaque model.
Abstract: An outbreak of coronavirus disease 2019 (COVID-19)1-3, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)4, has spread globally. Countermeasures are needed to treat and prevent further dissemination of the virus. Here we report the isolation of two specific human monoclonal antibodies (termed CA1 and CB6) from a patient convalescing from COVID-19. CA1 and CB6 demonstrated potent SARS-CoV-2-specific neutralization activity in vitro. In addition, CB6 inhibited infection with SARS-CoV-2 in rhesus monkeys in both prophylactic and treatment settings. We also performed structural studies, which revealed that CB6 recognizes an epitope that overlaps with angiotensin-converting enzyme 2 (ACE2)-binding sites in the SARS-CoV-2 receptor-binding domain, and thereby interferes with virus-receptor interactions by both steric hindrance and direct competition for interface residues. Our results suggest that CB6 deserves further study as a candidate for translation to the clinic.
1,141 citations
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TL;DR: PlatEMO as discussed by the authors is a MATLAB platform for evolutionary multi-objective optimization, which includes more than 50 multiobjective evolutionary algorithms and more than 100 multobjective test problems, along with several widely used performance indicators.
Abstract: Over the last three decades, a large number of evolutionary algorithms have been developed for solving multi-objective optimization problems. However, there lacks an upto-date and comprehensive software platform for researchers to properly benchmark existing algorithms and for practitioners to apply selected algorithms to solve their real-world problems. The demand of such a common tool becomes even more urgent, when the source code of many proposed algorithms has not been made publicly available. To address these issues, we have developed a MATLAB platform for evolutionary multi-objective optimization in this paper, called PlatEMO, which includes more than 50 multiobjective evolutionary algorithms and more than 100 multi-objective test problems, along with several widely used performance indicators. With a user-friendly graphical user interface, PlatEMO enables users to easily compare several evolutionary algorithms at one time and collect statistical results in Excel or LaTeX files. More importantly, PlatEMO is completely open source, such that users are able to develop new algorithms on the basis of it. This paper introduces the main features of PlatEMO and illustrates how to use it for performing comparative experiments, embedding new algorithms, creating new test problems, and developing performance indicators. Source code of PlatEMO is now available at: http://bimk.ahu.edu.cn/index.php?s=/Index/Software/index.html.
915 citations
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TL;DR: In this paper, the effect of Capsicum annuum L. proteins on the formation of silver nanoparticles was investigated using X-ray photoemission spectroscopy (XPS), electrochemical measurements, Fourier transform infrared (FTIR), and differential spectrum techniques.
855 citations
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TL;DR: A combinational measurement approach to event design and a new iterative event-triggered algorithm where continuous measurement of the neighbor states is avoided are proposed, which reduces the amount of communication and lowers the frequency of controller updates in practice.
689 citations
Authors
Showing all 17431 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yang Yang | 171 | 2644 | 153049 |
Ben Zhong Tang | 149 | 2007 | 116294 |
Shuai Liu | 129 | 1095 | 80823 |
Bo Wang | 119 | 2905 | 84863 |
Peng Wang | 108 | 1672 | 54529 |
Han-Qing Yu | 105 | 718 | 39735 |
Peng Chen | 103 | 918 | 43415 |
Rongchao Jin | 101 | 332 | 42920 |
Wei Zhang | 96 | 1404 | 43392 |
Peng Huang | 95 | 590 | 39098 |
Xuejun Wang | 95 | 725 | 43327 |
John H. Zhang | 84 | 895 | 29976 |
Hongwei Zhu | 81 | 486 | 27799 |
Chunxia Li | 80 | 206 | 20004 |
Lei Zhang | 78 | 1485 | 30058 |