S
Siddig Ibrahim Abdelwahab
Researcher at Jazan University
Publications - 150
Citations - 4361
Siddig Ibrahim Abdelwahab is an academic researcher from Jazan University. The author has contributed to research in topics: Apoptosis & Medicine. The author has an hindex of 36, co-authored 129 publications receiving 3544 citations. Previous affiliations of Siddig Ibrahim Abdelwahab include University of Malaya & Universiti Putra Malaysia.
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Journal ArticleDOI
In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot)
N.M. Isa,Siddig Ibrahim Abdelwahab,Syam Mohan,Ahmad Bustaman Abdul,Mohd Aspollah Sukari,Manal Mohamed Elhassan Taha,Suvitha Syam,Putri Narrima,S.Ch. Cheah,Syahida Ahmad,Mohd Rais Mustafa +10 more
TL;DR: The significant biological activities observed in this study indicated that boesenbergin A may be one of the agents responsible for the reported biological activities of B. rotunda crude extract.
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Protective mechanism of gallic acid and its novel derivative against ethanol-induced gastric ulcerogenesis: Involvement of immunomodulation markers, Hsp70 and Bcl-2-associated X protein
TL;DR: The in vivo antioxidant properties, immunomodulator proteins and inhibition of mitochondrial apoptosis may contribute to the gastroprotective activity of gallic acid (GA) and its novel synthetic derivative (GD).
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Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide, and anti-Helicobacter pylori activity.
Heyam Mohamed Ali Sidahmed,Ainnul Hamidah Syahadah Azizan,Syam Mohan,Mahmood Ameen Abdulla,Siddig Ibrahim Abdelwahab,Manal Mohamed Elhassan Taha,A. Hamid A. Hadi,Kamal Aziz Ketuly,Najihah Mohd Hashim,Mun Fai Loke,Jamuna Vadivelu +10 more
TL;DR: The current study reveals that DES demonstrated gastroprotective effects which could be attributed to its antioxidant effect, activation of HSP-70 protein, intervention with COX-2 inflammatory pathway and potent anti H pylori effect.
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Pyranocycloartobiloxanthone A, a novel gastroprotective compound from Artocarpus obtusus Jarret, against ethanol-induced acute gastric ulcer in vivo
Heyam Mohamed Ali Sidahmed,Najihah Mohd Hashim,Junaidah Amir,Mahmood Ameen Abdulla,A. Hamid A. Hadi,Siddig Ibrahim Abdelwahab,Manal Mohamed Elhassan Taha,Pouya Hassandarvish,Xinsheng Teh,Mun Fai Loke,Jamuna Vadivelu,Mawardi Rahmani,Syam Mohan +12 more
TL;DR: The results of the present study indicate that the gastroprotective effect of PA might contribute to the antioxidant and anti-inflammatory properties as well as the anti-apoptotic mechanism and antibacterial action against Helicobacter pylori.
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Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cells through the intrinsic pathway with involvement of NF-κB signalling and G0/G1 cell cycle arrest: a bioassay-guided approach.
Ismail Adam Arbab,Ahmad Bustamam Abdul,Mohd Aspollah Sukari,Rasedee Abdullah,Suvitha Syam,Suvitha Syam,Behnam Kamalidehghan,Mohamed Yousif Ibrahim,Manal Mohamed Elhassan Taha,Siddig Ibrahim Abdelwahab,Hapipah Mohd Ali,Syam Mohan +11 more
TL;DR: The results demonstrated that the DTN isolated from Clausena excavata inhibited the proliferation of MCF-7 cells, leading to cell cycle arrest and programmed cell death, which was confirmed to occur through the mitochondrial pathway with involvement of the NF-κB signalling pathway.