M
Mun Fai Loke
Researcher at University of Malaya
Publications - 68
Citations - 1983
Mun Fai Loke is an academic researcher from University of Malaya. The author has contributed to research in topics: Helicobacter pylori & Microbiome. The author has an hindex of 21, co-authored 66 publications receiving 1487 citations. Previous affiliations of Mun Fai Loke include Boston Children's Hospital & National University of Singapore.
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High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia.
Julia L. Drewes,James R. White,Christine M. Dejea,Payam Fathi,Thevambiga Iyadorai,Jamuna Vadivelu,April Camilla Roslani,Elizabeth C. Wick,Emmanuel F. Mongodin,Mun Fai Loke,Kumar Thulasi,Han Ming Gan,Khean-Lee Goh,Hoong Yin Chong,Sandip Kumar,Jane W. Wanyiri,Cynthia L. Sears +16 more
TL;DR: Researchers in the USA and Malaysia found that bowel cancers were enriched in invasive bacterial biofilms as well as several specific gut and oral species, including one - Fusobacterium nucleatum - known to promote tumorigenesis in mouse models.
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Biogenic synthesis, characterization of antibacterial silver nanoparticles and its cell cytotoxicity
V. Gopinath,V. Gopinath,S. Priyadarshini,Mun Fai Loke,J. Arunkumar,Enrico Marsili,Davoodbasha MubarakAli,Davoodbasha MubarakAli,Palaniyandi Velusamy,Jamuna Vadivelu +9 more
TL;DR: This study evidenced that biogenic nanoparticles could affect the bacterial replication, protein leakage and eventually cell death, and might be used for active antimicrobial agents for the chronic infections.
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Helicobacter pylori Eradication Causes Perturbation of the Human Gut Microbiome in Young Adults.
Theresa Wan-Chen Yap,Han Ming Gan,Yin Peng Lee,Alex Hwong Ruey Leow,Ahmad Najib Azmi,Ahmad Najib Azmi,Fritz Francois,Guillermo I. Perez-Perez,Mun Fai Loke,Khean-Lee Goh,Jamuna Vadivelu +10 more
TL;DR: The preliminary stool metagenomics study shows that eradication of H. pylori caused perturbation of the gut microbiome and may indirectly affect the health of human.
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Helicobacter pylori infection is associated with worse severity of Parkinson's disease
Ai Huey Tan,Sanjiv Mahadeva,Connie Marras,Abdul Malik Thalha,Chiun Khang Kiew,Chia Ming Yeat,Sheang Wen Ng,Sheau Phing Ang,Siew Kian Chow,Mun Fai Loke,Jamunarani Vadivelu,Norlinah Mohamed Ibrahim,Hoi Sen Yong,Chong Tin Tan,Susan H. Fox,Anthony E. Lang,Shen-Yang Lim +16 more
TL;DR: This is the largest cross-sectional study to demonstrate an association between HP positivity and worse PD motor severity and HP status demonstrated significant main effects on UPDRS Part III and timed gait.
Journal ArticleDOI
Culturable Bacterial Microbiota of the Stomach of Helicobacter pylori Positive and Negative Gastric Disease Patients
Yalda Khosravi,Yakhya Dieye,Bee Hoon Poh,Chow Goon Ng,Mun Fai Loke,Khean-Lee Goh,Jamuna Vadivelu +6 more
TL;DR: It is suggested that there may be geographical variations in the diversity of the human gastric microbiome and possible interactions between Hp and other bacterial species from stomach microbiota in pathogenesis are proposed for further investigations.