Silvia Caballero

TL;DR: It is shown that antibiotic-induced alterations in the intestinal flora reduce ischemic brain injury in mice, an effect transmissible by fecal transplants, and that IL-10 and IL-17 are required for the neuroprotection afforded by intestinal dysbiosis.

TL;DR: An underappreciated risk is demonstrated for the treatment of allo-HSCT recipients with antibiotics that may exacerbate GVHD in the colon, and this study suggests that not all antibiotic regimens are appropriate for treating transplant patients.

TL;DR: It is demonstrated that reintroduction of a diverse intestinal microbiota to densely VRE-colonized mice eliminates VRE from the intestinal tract and indicates that obligate anaerobic bacteria belonging to the Barnesiella genus enable clearance of intestinal VRE colonization and may provide novel approaches to prevent the spread of highly antibiotic-resistant bacteria.

TL;DR: This review summarizes recent work characterizing commensal microbes that contribute to the antimicrobial defense/inflammation axis.

TL;DR: These findings suggest that therapeutic or prophylactic administration of defined bacterial consortia to individuals with compromised microbiota composition may reduce inter-patient transmission and intra-patient dissemination of highly antibiotic-resistant pathogens.