R
Rebecca A. Carter
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 14
Citations - 1295
Rebecca A. Carter is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Colonisation resistance & Innate immune system. The author has an hindex of 11, co-authored 14 publications receiving 988 citations. Previous affiliations of Rebecca A. Carter include Kettering University.
Papers
More filters
Journal ArticleDOI
Cooperating Commensals Restore Colonization Resistance to Vancomycin-Resistant Enterococcus faecium
Silvia Caballero,Sohn Kim,Rebecca A. Carter,Ingrid Leiner,Bože Sušac,Liza Miller,Grace Kim,Lilan Ling,Eric G. Pamer,Eric G. Pamer +9 more
TL;DR: These findings suggest that therapeutic or prophylactic administration of defined bacterial consortia to individuals with compromised microbiota composition may reduce inter-patient transmission and intra-patient dissemination of highly antibiotic-resistant pathogens.
Journal ArticleDOI
Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection.
Michael C. Abt,Brittany B. Lewis,Silvia Caballero,Huizhong Xiong,Rebecca A. Carter,Bože Sušac,Lilan Ling,Ingrid Leiner,Eric G. Pamer +8 more
TL;DR: A critical role for ILC1s in defense against C. difficile is demonstrated and protection against infection was restored by transferring ILCs into Ragγc(-/-) mice.
Journal ArticleDOI
Loss of Microbiota-Mediated Colonization Resistance to Clostridium difficile Infection With Oral Vancomycin Compared With Metronidazole
Brittany B. Lewis,Charlie G. Buffie,Rebecca A. Carter,Ingrid Leiner,Nora C. Toussaint,Liza Miller,Asia Gobourne,Lilan Ling,Eric G. Pamer +8 more
TL;DR: Investigation of the effect of brief treatment with metronidazole and/or oral vancomycin on susceptibility to C. difficile infection in mice demonstrated that vancomYcin, and to a lesser extent metronidsazole, are associated with marked intestinal microbiota destruction and greater risk of colonization by nosocomial pathogens.
Journal ArticleDOI
Commensal microbes provide first line defense against Listeria monocytogenes infection.
Simone Becattini,Eric R. Littmann,Rebecca A. Carter,Sohn Kim,Sejal Morjaria,Lilan Ling,Yangtsho Gyaltshen,Emily Fontana,Ying Taur,Ingrid Leiner,Eric G. Pamer +10 more
TL;DR: It is shown that a diverse microbiota markedly reduces Listeria monocytogenes colonization of the gut lumen and prevents systemic dissemination, and identifies intestinal commensal species that, by enhancing resistance against this pathogen, represent potential probiotics.
Journal ArticleDOI
Innate Lymphocyte/Ly6Chi Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance
Huizhong Xiong,James W. Keith,Dane Samilo,Dane Samilo,Rebecca A. Carter,Ingrid Leiner,Eric G. Pamer +6 more
TL;DR: It is demonstrated that inflammatory monocytes are rapidly recruited to the lungs of K. pneumoniae-infected mice and produce TNF, which markedly increases the frequency of IL-17-producing innate lymphoid cells, indicating that innate lymphocytes engage in a positive-feedback loop with monocytes that promotes clearance of pneumonia.