L
Lilan Ling
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 34
Citations - 6908
Lilan Ling is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Transplantation & Colonisation resistance. The author has an hindex of 23, co-authored 32 publications receiving 5069 citations. Previous affiliations of Lilan Ling include Kettering University.
Papers
More filters
Journal ArticleDOI
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.
Charlie G. Buffie,Vanni Bucci,Vanni Bucci,Richard R. Stein,Peter T. McKenney,Lilan Ling,Asia Gobourne,Daniel No,Hui Liu,Melissa A. Kinnebrew,Agnes Viale,Eric R. Littmann,Marcel R.M. van den Brink,Marcel R.M. van den Brink,Robert R. Jenq,Ying Taur,Chris Sander,Justin R. Cross,Nora C. Toussaint,Nora C. Toussaint,Joao B. Xavier,Joao B. Xavier,Eric G. Pamer,Eric G. Pamer +23 more
TL;DR: It is determined that Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium, is associated with resistance to C. difficile infection and, upon administration, enhances resistance to infection in a secondary bile Acid dependent fashion.
Journal ArticleDOI
Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis.
Krista Dubin,Margaret K. Callahan,Boyu Ren,Raya Khanin,Agnes Viale,Lilan Ling,Daniel No,Asia Gobourne,Eric R. Littmann,Curtis Huttenhower,Curtis Huttenhower,Eric G. Pamer,Eric G. Pamer,Jedd D. Wolchok +13 more
TL;DR: It is demonstrated that increased representation of bacteria belonging to the Bacteroidetes phylum is correlated with resistance to the development of checkpoint-blockade-induced colitis, and a paucity of genetic pathways involved in polyamine transport and B vitamin biosynthesis is associated with an increased risk of colitis.
Journal ArticleDOI
The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.
Ying Taur,Ying Taur,Robert R. Jenq,Robert R. Jenq,Miguel-Angel Perales,Miguel-Angel Perales,Eric R. Littmann,Sejal Morjaria,Lilan Ling,Daniel No,Asia Gobourne,Agnes Viale,Parastoo B. Dahi,Parastoo B. Dahi,Doris M. Ponce,Doris M. Ponce,Juliet N. Barker,Juliet N. Barker,Sergio Giralt,Sergio Giralt,Marcel R.M. van den Brink,Marcel R.M. van den Brink,Marcel R.M. van den Brink,Eric G. Pamer +23 more
TL;DR: The results indicate that the intestinal microbiota may be an important factor in the success or failure in allo-HSCT, and the diversity of the intestine microbiota at engraftment is an independent predictor of mortality in recipients.
Journal ArticleDOI
Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells.
Corinne Benakis,David Brea,Silvia Caballero,Giuseppe Faraco,Jamie Moore,Michelle Murphy,Giulia Sita,Gianfranco Racchumi,Lilan Ling,Eric G. Pamer,Eric G. Pamer,Costantino Iadecola,Josef Anrather +12 more
TL;DR: It is shown that antibiotic-induced alterations in the intestinal flora reduce ischemic brain injury in mice, an effect transmissible by fecal transplants, and that IL-10 and IL-17 are required for the neuroprotection afforded by intestinal dysbiosis.
Journal ArticleDOI
Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease
Robert R. Jenq,Robert R. Jenq,Ying Taur,Ying Taur,Sean M. Devlin,Doris M. Ponce,Doris M. Ponce,Jenna D. Goldberg,Jenna D. Goldberg,Katya F. Ahr,Eric R. Littmann,Lilan Ling,Asia Gobourne,Liza Miller,Melissa D. Docampo,Jonathan U. Peled,Jonathan U. Peled,Nicholas Arpaia,Justin R. Cross,Tatanisha Peets,Melissa Lumish,Yusuke Shono,Jarrod A Dudakov,Hendrik Poeck,Alan M. Hanash,Alan M. Hanash,Juliet N. Barker,Juliet N. Barker,Miguel-Angel Perales,Miguel-Angel Perales,Sergio Giralt,Sergio Giralt,Eric G. Pamer,Eric G. Pamer,Marcel R.M. van den Brink,Marcel R.M. van den Brink +35 more
TL;DR: It is concluded that increased abundance of commensal bacteria belonging to the Blautia genus is associated with reduced lethal GVHD and improved overall survival.