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Silvio E. Inzucchi
Researcher at Yale University
Publications - 511
Citations - 64889
Silvio E. Inzucchi is an academic researcher from Yale University. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 92, co-authored 424 publications receiving 54101 citations. Previous affiliations of Silvio E. Inzucchi include University of Toronto & American Diabetes Association.
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Journal Article
Abstract 13520: Empagliflozin Reduces Markers of Arterial Stiffness, Vascular Resistance and Cardiac Workload in EMPA-REG OUTCOME
Robert J. Chilton,Lars Gullestad,David Fitchett,Silvio E. Inzucchi,Michaela Mattheus,Hans-Juergen Woerle,Odd Erik Johansen +6 more
TL;DR: In EMPA-REG OUTCOME®, empagliflozin added to standard of care in patients with type 2 diabetes and established vascular disease, significantly reduced the primary composite outcome of EMT.
Journal ArticleDOI
Liver tests and outcomes in heart failure with reduced ejection fraction: findings from DAPA‐HF
Carly L. Adamson,Lorna M Cowan,W. De Boer,Mirta Diez,Jarosław Drożdż,Andrej Dukát,Silvio E. Inzucchi,Lars Køber,Mikhail Kosiborod,Charlotta Ljungman,Felipe Martinez,Piotr Ponikowski,Marc S. Sabatine,Dan Lindholm,Olof Bengtsson,David W. Boulton,Peter J. Greasley,Anna Maria Langkilde,Mikaela Sjöstrand,Scott D. Solomon,John J.V. McMurray,Pardeep S. Jhund +21 more
TL;DR: Bilirubin concentration was an independent predictor of worse outcomes but did not modify the benefits of dapagliflozin in HFrEF, and DAPA-HF was not associated with change in liver tests.
Journal ArticleDOI
Extrapolating Long-term Event-Free and Overall Survival With Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction: An Exploratory Analysis of a Phase 3 Randomized Clinical Trial.
Kieran F. Docherty,Pardeep S. Jhund,Brian Claggett,João Pedro Ferreira,João Pedro Ferreira,Olof Bengtsson,Silvio E. Inzucchi,Lars Køber,Mikhail Kosiborod,Mikhail Kosiborod,Anna Maria Langkilde,Felipe Martinez,Piotr Ponikowski,Marc S. Sabatine,Mikaela Sjöstrand,Scott D. Solomon,John J.V. McMurray,David L. DeMets,Mirta Diez,Jose C. Nicolau,Tzvetana Katova,Jonathan G. Howlett,Eileen O'Meara,Subodh Verma,Junbo Ge,Jan Belohlavek,Morten Schou,Michael Böhm,Béla Merkely,Vijay K. Chopra,Masahumi Kitakaze,Rudolf A. de Boer,Jarosław Drożdż,Tereshchenko Sn,Andrej Dukát,Charlotta Ljungman,Chern-En Chiang,Mark C. Petrie,Inder S. Anand,Akshay S. Desai,Pham Nguyen Vinh,S Sassone,D Aizenberg,M Talavera,G Mercau,D Martinez,J Albisu,A Hershson,R García Durán,M Hominal,N Cluigt,F Colombo Berra,E Perna,R Ahuad Guerrero,D García Brasca,C Zaidman,C Majul,J Taborda,H Luquez,J Sala,A Sosa Liprandi,G Cursack,O Montaña,A Fernandez,M Najenson,S Nani,G Caruso,E Fairman,S Pereiro Gonzalez,L Maia,A Pereira,P Rossi,D Precoma,F Neuenschwander,G Reis,F Guimaraes,J Saraiva,F Arantes,M Hernandes,J Borges,B Paolino,E Vasconcellos,E Manenti,P Pimentel,P Leaes,S Rassi,T Dalcoquio,T Katova,D Avramov,N Spasova,D Raev,B Chompalova,M Milanova,M Tokmakova,N Runev,A Mihov,A Gogov,A Dincheva,N Iliev,B Kolomanov,Y Ivanova,K Ilieva,D Karageorgiev,I Efremov,N Botushanov,S Vladeva,C Constance,S Vizel,A Pandey,D Phaneuf,S Mehta,D Rupka,Y Pesant,P Poirier,R Chehayeb,M Babapulle,E O’Meara,J Howlett,L Yao,Robert S. McKelvie,S Verma,M Hartleib,R Vijayaraghavan,J Vyselaar,F Azzari,J Cha,F Nasser-Sharif,T.Z. Maung,S Mansour,Y Khaykin,R Lee,P Fong,H Jiang,X Li,L Fu,Y Li,D Wang,Q Zhao,Y Dong,Y Zhou,X Lin,J Dong,X Zhang,Z Zheng,W Huang,Y Gu,J Liu,X Guo,L Wu,Q Tang,D Peng,W Dong,Y Liang,Z Li,Z Wang,B Han,C Wu,J Belohlavek,J Slaby,J Spinar,P Hajek,L Busak,J Carda,L Spinarova,I Malek,J Skopek,R Kuchar,E Krcova,O Mayer,D Kucera,M Schou,L Køber,K Egstrup,J Hove,G Gislason,L Videbæk,M Böhm,R Nischik,N Toursarkissian,K Appel,E Schmidt,I Weigmann,M Kellerer,A Al-Zoebi,U Stephan,A Wilke,S Genth-Zotz,G Simonis,D Tschöpe,A Costard-Jäckle,B Merkely,P Andrássy,E Noori,Z Járai,F Poór,C Király,A Czigány,L Nagy,Á Motyovszki,G Masszi,V Mehta,V Chopra,A Naik,M Gadkari,R Sawant,M Mahapekar,S Karna,M Deshpande,V Bhargava,V Kothiwale,J Menon,D Sinha,S Sinha,H Kokane,P Udgire,M Sandhu,M Suzuki,M Nishino,A Kiyosue,K Sumii,S Suzuki,Y Noguchi,S Tanaka,H Takase,M Mohri,S Higashiue,N Fujimoto,H Iseki,T Kuramochi,T Shibasaki,H Tsutsui,Y Takagi,Y Katayama,N Takeyasu,T Anzai,H Nagashima,A Kimura,T Kakuta,T Hashimoto,H Sugino,K Saito,S Hiroi,H Kamiya,K Fukui,S Matsuoka,K Moritani,Y Tomobuchi,Y Hata,R Kawamura,E Hattori,K Fujimoto,N Takahashi,W Takahashi,T Kadokami,H Ueno,S Uchikawa,T Shinozaki,Y Onishi,N Komiyama,S Inoue,Y Momiyama,Y Ueda,Y Komura,T Arakawa,H Meno,M Higuchi,Y Hayashi,K Seki,K Fujii,K Harada,A Wada,T Kasai,K Kuwahara,Y Yasaka,I Uchida,Y Okumura,Y Hisamatsu,T Nunohiro,K Tsukahara,A Hirohata,M Asakura,R De Boer,L Bellersen,H Swart,B Groenemeijer,S Zoet Nugteren,C De Nooijer,P Nierop,R Robles De Medina,J Van Eck,M Van Hessen,J Drożdż,P Miękus,R Ściborski,B Mikłaszewicz,W Sudnik,R Mariankowski,R Witek,G Drelich,E MirekBryniarska,S Szynal,L Pawłowicz,J Lampart,R Korzeniak,J Prokopczuk,S Boldueva,Y Didenko,N Dzhaiani,L Ermoshkina,V Kostenko,E Vishneva,N Koziolova,S Tereschenko,D Pevzner,L Krylova,A Chernyavsky,A Kazakov,S Aksentiev,R Nilk,Z Paltsman,A Galyavich,A Maltcev,P Kopylov,A Ezhov,J Shilko,L Antalik,V Bugan,P Fulop,L Jamriskova,D Kollarova,V Macek,M Slovenska,L Tomasova,D Vinanska,R Smik,J Selecky,I Majercak,P Olexa,C Ljungman,A Hedman,C Lindholm,K Lindmark,T Mooe,C Chiang,L Lin,M Liu,K Chang,C Hsia,J Shih,P Liu,T Lin,H Chang,J Huang,I Hsieh,W Tseng,M Petrie,R Gardner,A Clark,A Japp,P Jhund,C Lang,S Leslie,Clare Murphy,Colin J. Petrie,J Walsh,A Arif,D Avino,S Banerjee,M Kanwar,M Berk,C Brown,C Ince,T Lewis,A Nikfarjam,J Patel,K Ramanathan,A Schabauer,T Greene,K Shah,R Sotolongo,A Viera,O Akinboboye,A Arouni,B Bertolet,L Chandra,T Cimato,S Deleon,M Bennett,F Franchi,G Hamroff,D Hotchkiss,M Jardula,J Javier,N Kazemi,J Kostis,J Lash,L Levinson,I Lieber,E Lo,S Mahal,R Manshadi,F Mody,A Paraschos,M Pursley,G Hickey,J Londono,D Singal,S Srivastava,J Teel,J Castriz,L Kantaros,C Venugopal,C Staniloae,D Gupta,F Syed,M Zacharias,N Jaffrani,P Wakefield,M Nassif,T Haddad,S Iskander,G Lewis,B Al-Joundi,W French,M Ogunniyi,S Emani,S Weiss,R Cheng,V Florea,S Joseph,S Lederman,J Izzo,M Bernstein,E Fruehling,B Foley,L Younis,D Song,V Pham,H Nguyen,H Do,B Truong,T Nguyen,D Ho,Dapa-Hf Investigators,Committees +444 more
TL;DR: In this article, the authors performed exploratory analysis of Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure (DAPA-HF), a phase 3 randomized, placebo-controlled clinical trial conducted at 410 sites in 20 countries.
Journal ArticleDOI
Empagliflozin and Decreased Risk of Nephrolithiasis: A Potential New Role for SGLT2 Inhibition?
Priyadarshini Balasubramanian,Christoph Wanner,João Pereira,Anne Pernille Ofstad,Amelie Elsaesser,Bernard Zinman,Silvio E. Inzucchi +6 more
TL;DR: Compared with placebo, empagliflozin therapy was associated with an approximate 40% reduced risk of urinary tract stone events in T2D patients, which may involve altered lithogenic profile of the urine.
Journal ArticleDOI
The reliability of in-hospital diagnoses of diabetes mellitus in the setting of an acute myocardial infarction
Suzanne V. Arnold,Kasia J. Lipska,Silvio E. Inzucchi,Yan Li,Philip G. Jones,Darren K. McGuire,Abhinav Goyal,Joshua M. Stolker,Marcus Lind,John A. Spertus,Mikhail Kosiborod +10 more
TL;DR: Two potential selective screening methods for DM in the setting of AMI are established that could identify the vast majority of incident DM by targeted screening of 40–50% of patients with AMI with HbA1c testing.