J
João Pereira
Researcher at Yale University
Publications - 296
Citations - 8601
João Pereira is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 33, co-authored 180 publications receiving 7138 citations. Previous affiliations of João Pereira include Universidade Nova de Lisboa & Technical University of Lisbon.
Papers
More filters
Journal ArticleDOI
Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate
Rajita Pappu,Susan R. Schwab,Ivo Cornelissen,João Pereira,Jean B. Regard,Ying Xu,Eric Camerer,Yaowu Zheng,Yong Huang,Jason G. Cyster,Shaun R. Coughlin +10 more
TL;DR: Separate sources provide S1P to plasma and lymph to help lymphocytes exit the low-S1P environment of lymphoid organs, and disruption of compartmentalized S 1P signaling is a plausible mechanism by which S1p-receptor-1 agonists function as immunosuppressives.
Journal ArticleDOI
Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients
TL;DR: It is concluded that lymphocyte egress is mediated by S 1P gradients that are established by S1P lyase activity and that the lyase may represent a novel immunosuppressant drug target.
Journal ArticleDOI
An update to the systematic literature review of empirical evidence of the impacts and outcomes of computer games and serious games
Elizabeth Boyle,Thomas Hainey,Thomas Connolly,Grant Gray,Jeffrey Earp,Michela Ott,Theodore Lim,Manuel Ninaus,Cláudia Ribeiro,João Pereira +9 more
TL;DR: Future research on digital games would benefit from a systematic programme of experimental work, examining in detail which game features are most effective in promoting engagement and supporting learning.
Journal ArticleDOI
Equity in the finance of health care: some further international comparisons
Adam Wagstaff,Eddy van Doorslaer,Hattem Van Der Burg,Samuel Calonge,Terkel Christiansen,Guido Citoni,Ulf-G Gerdtham,Michael Gerfin,Lorna Gross,Unto Häkinnen,Paul Johnson,Jürgen John,Jan Klavus,Claire Lachaud,Jørgen Lauritsen,Robert E. Leu,Brian Nolan,Encarna Peran,João Pereira,Carol Propper,Frank Puffer,Lise Rochaix,Marisol Rodríguez,Martin Schellhorn,Gun Sundberg,Olaf Winkelhake +25 more
TL;DR: This paper presents further international comparisons of progressivity of health care financing systems, modifying the methodology used there and achieving a higher degree of cross-country comparability in variable definitions, and updating and extending the cross-section of countries.
Journal ArticleDOI
Oxysterols direct immune cell migration via EBI2
Sébastien Hannedouche,Juan Zhang,Tangsheng Yi,Weijun Shen,Weijun Shen,Deborah Nguyen,João Pereira,Danilo Guerini,Birgit Baumgarten,Silvio Roggo,Ben Wen,Richard Knochenmuss,Sophie Noël,François Gessier,Lisa M. Kelly,Miroslava Vanek,Stephane Laurent,Inga Preuss,Charlotte Miault,Isabelle Christen,Ratnaningrum Karuna,Wei Li,Dong-In Koo,Thomas Suply,Christian Schmedt,Eric C. Peters,Rocco Falchetto,Andreas Katopodis,Carsten Spanka,Marie-Odile Roy,Michel Detheux,Yu Chen,Peter G. Schultz,Charles Y. Cho,Klaus Seuwen,Jason G. Cyster,Andreas W. Sailer +36 more
TL;DR: The identification of 7α,25-dihydroxycholesterol as a potent and selective agonist of EBI2 and its role in the adaptive immune response is described.