S
Sima Rafati
Researcher at Pasteur Institute of Iran
Publications - 179
Citations - 4950
Sima Rafati is an academic researcher from Pasteur Institute of Iran. The author has contributed to research in topics: Cutaneous leishmaniasis & Leishmania major. The author has an hindex of 37, co-authored 173 publications receiving 4358 citations. Previous affiliations of Sima Rafati include Pasteur Institute.
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Improvement of different vaccine delivery systems for cancer therapy.
TL;DR: Different vaccine delivery systems for prevention or treatment of cancer, including nanoparticles (NPs), have emerged as effective vaccine adjuvants for infectious diseases and cancer therapy and their clinical applications and the future prospects for cancer vaccine development are discussed.
Journal Article
Leishmaniasis vaccine candidates for development: a global overview.
TL;DR: This review presents only the vaccines in use and those in development for use in dogs or humans, and is not an exhaustive review of vaccine discovery or the principles of clinical immunology underlying vaccine development.
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Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis
Adnene Salhi,Virmondes Rodrigues,Ferrucio Santoro,Hélia Dessein,Audrey Romano,Lúcio Roberto Cançado Castellano,Mathieu Sertorio,Sima Rafati,Christophe Chevillard,Aluisio Prata,Alexandre Alcaïs,Laurent Argiro,Alain Dessein +12 more
TL;DR: An important role for IL-10 in skin lesions in humans infected with L. braziliensis is demonstrated, and circulating monocytes and Tregs are identified as principal sources of IL-819C/C in these patients.
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Protective vaccination against experimental canine visceral leishmaniasis using a combination of dna and protein immunization with cysteine proteinases type i and ii of l. infantum
Sima Rafati,Alireza Nakhaee,Tahere Taheri,Yasaman Taslimi,Haideh Darabi,Davood Eravani,Stephanie L. Sanos,Paul M. Kaye,Mohammad Taghikhani,Mohammad Taghikhani,Shahram Jamshidi,Mohammad Ali Rad +11 more
TL;DR: It is proposed that the combination of DNA and recombinant protein vaccination using CPs could be instrumental to control (VL) in dogs.
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A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major.
TL;DR: This is the first report demonstrating that co-injection of two genes expressing different antigens induces a long lasting protective response, whereas the separate injection of cysteine proteases genes is not protective.