J
Jean Pierre Pignon
Researcher at Université Paris-Saclay
Publications - 49
Citations - 8254
Jean Pierre Pignon is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Lung cancer & Hazard ratio. The author has an hindex of 31, co-authored 49 publications receiving 7164 citations. Previous affiliations of Jean Pierre Pignon include AstraZeneca & Institut Gustave Roussy.
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Journal ArticleDOI
Lung Adjuvant Cisplatin Evaluation: A Pooled Analysis by the LACE Collaborative Group
Jean Pierre Pignon,Hélène Tribodet,Giorgio V. Scagliotti,Jean-Yves Douillard,Frances A. Shepherd,Richard J. Stephens,Ariane Dunant,Valter Torri,Rafael Rosell,Lesley Seymour,Stephen G. Spiro,Estelle Rolland,Roldano Fossati,Delphine Aubert,Keyue Ding,David A. Waller,Thierry Le Chevalier +16 more
TL;DR: Postoperative cisplatin-based chemotherapy significantly improves survival in patients with non-small-cell lung cancer (NSCLC).
Journal ArticleDOI
A meta-analysis of thoracic radiotherapy for small-cell lung cancer.
Jean Pierre Pignon,Rodrigo Arriagada,Daniel C. Ihde,David H. Johnson,Michael C. Perry,Robert L. Souhami,Ola Brodin,Rudolf A. Joss,Merrill S. Kies,Bernard Lebeau,Taisuke Onoshi,Kell Østerlind,Martin H.N. Tattersall,Henry Wagner +13 more
TL;DR: Thoracic radiotherapy moderately improves survival in patients with limited small-cell lung cancer who are treated with combination chemotherapy, and identification of the optimal combination of chemotherapy and radiotherapy will require further trials.
Journal ArticleDOI
Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients
Bertrand Baujat,Hélène Audry,Jean Bourhis,Anthony T.C. Chan,Haluk Onat,Daniel T.T. Chua,Dora L.W. Kwong,Muhyi Al-Sarraf,Kwan Hwa Chi,Masato Hareyama,Sing Fai Leung,Kullathorn Thephamongkhol,Jean Pierre Pignon +12 more
TL;DR: Chemotherapy led to a small, but significant, benefit for overall survival and event-free survival when chemotherapy was administered concomitantly with RT.
Journal ArticleDOI
Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis
Pierre Blanchard,Pierre Blanchard,Anne W.M. Lee,Sophie Marguet,Julie Leclercq,Wai Tong Ng,Jun Ma,Anthony T.C. Chan,Pei Yu Huang,Ellen Benhamou,Ellen Benhamou,Guopei Zhu,Daniel T.T. Chua,Yong Chen,Hai-Qiang Mai,Dora L.W. Kwong,Shie Lee Cheah,James J. Moon,Yuk Tung,Kwan-Hwa Chi,George Fountzilas,Li Zhang,Edwin P. Hui,Taixiang Lu,Jean Bourhis,Jean Pierre Pignon,Jean Pierre Pignon +26 more
TL;DR: The results confirm that the addition of concomitant chemotherapy to radiotherapy significantly improves survival in patients with locoregionally advanced nasopharyngeal carcinoma.
Journal ArticleDOI
ERCC1 Isoform Expression and DNA Repair in Non-Small-Cell Lung Cancer
Luc Friboulet,Ken A. Olaussen,Ken A. Olaussen,Jean Pierre Pignon,Frances A. Shepherd,Ming-Sound Tsao,Stephen L. Graziano,Robert A. Kratzke,Jean-Yves Douillard,Lesley Seymour,Robert Pirker,Martin Filipits,Fabrice Andre,Fabrice Andre,Eric Solary,Eric Solary,Florence Ponsonnailles,Florence Ponsonnailles,Angélique Robin,Angélique Robin,Annabelle Stoclin,Annabelle Stoclin,Nicolas Dorvault,Nicolas Dorvault,Frédéric Commo,Frédéric Commo,Julien Adam,Julien Adam,Elsa Vanhecke,Elsa Vanhecke,Patrick Saulnier,Jürgen Thomale,Thierry Le Chevalier,Thierry Le Chevalier,Ariane Dunant,Vanessa Rousseau,Gwénaël Le Teuff,Elisabeth Brambilla,Jean-Charles Soria,Jean-Charles Soria +39 more
TL;DR: It was found that none of the 16 antibodies could distinguish among the four ERCC1 protein isoforms, whereas only one isoform produced a protein that had full capacities for nucleotide excision repair and cisplatin resistance.