S
Sofie Bekaert
Researcher at Ghent University
Publications - 77
Citations - 3684
Sofie Bekaert is an academic researcher from Ghent University. The author has contributed to research in topics: Population & Telomere. The author has an hindex of 29, co-authored 77 publications receiving 3300 citations. Previous affiliations of Sofie Bekaert include Ghent University Hospital.
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Journal ArticleDOI
Leukocyte telomere length and diet in the apparently healthy, middle-aged Asklepios population
Tim De Meyer,Sofie Bekaert,Marc De Buyzere,Dirk De Bacquer,Michel Langlois,Nitin Shivappa,James R. Hébert,Thierry C. Gillebert,Ernst Rietzschel,Inge Huybrechts,Inge Huybrechts +10 more
TL;DR: An at most limited association between overall dietary patterns and telomere length in the general population is suggested, and the association between telomeres length and deep fried potato product intake warrants additional research.
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Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells
Khalil Abou-El-Ardat,Pieter Monsieurs,Natasa Anastasov,Michael J. Atkinson,Hanane Derradji,Tim De Meyer,Sofie Bekaert,Wim Van Criekinge,Sarah Baatout +8 more
TL;DR: The results point to the fact that a low dose of X-rays seems to have a significant proliferative effect on normal thyroids, which should be studied further as opposed to its effect on RET/PTC-positive thyroid systems which was subtle, anti-proliferative and system-dependent.
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Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.
Hanane Derradji,Sofie Bekaert,Tim De Meyer,P. Jacquet,Khalil Abou-El-Ardat,Myriam Ghardi,Michaux Arlette,Sarah Baatout +7 more
TL;DR: In this paper, the authors found that irradiated fetuses with forelimb defects exhibited excessive apoptosis in the predigital regions and showed a marked telomere shortening.
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Associations between single nucleotide polymorphisms in thyroid hormone transporter genes (MCT8, MCT10 and OATP1C1) and circulating thyroid hormones.
Greet Roef,Ernst Rietzschel,Tim De Meyer,Sofie Bekaert,Marc De Buyzere,Caroline M. Van daele,Kaatje Toye,Jean-Marc Kaufman,Youri Taes +8 more
TL;DR: Two SNPs in MCT8 were related to circulating thyroid hormone levels in men but not in women: the rs5937843 polymorphism (G/T) was inversely associated with FT4 levels and the rs6647476 (T/C) polymorphism related negatively to circulating FT3.
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Relation between telomerase activity, hTERT and telomere length for intracranial tumours.
Lode Maes,L. Van Neste,K. Van Damme,Jean-Pierre Kalala,L. De Ridder,Sofie Bekaert,Maria Cornelissen +6 more
TL;DR: Results indicate that telomere shortening may be a critical step in pathogenesis of atypical and malignant meningiomas and gliomas, and critical telomeres shortening in vitro was shown to activate telomerase.