S
Sofie Bekaert
Researcher at Ghent University
Publications - 77
Citations - 3684
Sofie Bekaert is an academic researcher from Ghent University. The author has contributed to research in topics: Population & Telomere. The author has an hindex of 29, co-authored 77 publications receiving 3300 citations. Previous affiliations of Sofie Bekaert include Ghent University Hospital.
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Journal ArticleDOI
Corrigendum to "Reproducibility of Telomere Length Assessment - An International Collaborative Study" [International Journal of Epidemiology 2014, doi: 10.1093/ije/dyu191]
Carmen Martin-Ruiz,Duncan M. Baird,Laureline Roger,Petra Boukamp,Damir Krunic,Richard M. Cawthon,Martin M Dokter,Pim van der Harst,Sofie Bekaert,Tim De Meyer,Göran Roos,Ulrika Svenson,Veryan Codd,Nilesh J. Samani,Liane M. McGlynn,Paul G. Shiels,Karen A. Pooley,Alison M. Dunning,Rachel Cooper,Andrew Wong,Andrew Kingston,Thomas von Zglinicki +21 more
Journal ArticleDOI
Telomere shortening is associated with malformation in p53-deficient mice after irradiation during specific stages of development.
Sofie Bekaert,Hanane Derradji,Tim De Meyer,Arlette Michaux,J. Buset,Mieke Neefs,Max Mergeay,P. Jacquet,Patrick Van Oostveldt,Sarah Baatout +9 more
TL;DR: A hypothesis is formulated in which telomere shortening is linked to the absence of p53 in mouse foetuses and that when, in the presence of shorter telomeres, these Foetuses are irradiated, the chance for the occurrence of developmental defects increases substantially.
Journal ArticleDOI
No Shorter Telomeres in Subjects With a Family History of Cardiovascular Disease in the Asklepios Study
Tim De Meyer,Caroline M. Van daele,Marc De Buyzere,Simon Denil,Dirk De Bacquer,Patrick Segers,Luc Cooman,Guy De Backer,Thierry C. Gillebert,Sofie Bekaert,Ernst Rietzschel +10 more
TL;DR: These findings cast serious doubt on the hypothesis that telomere length is shorter in families with an increased risk of CVD and do not support the Telomere Hypothesis ofCVD.
Journal ArticleDOI
Modest opposite associations of endogenous testosterone and oestradiol with left ventricular remodelling and function in healthy middle‐aged men
Johannes Ruige,Ernst Rietzschel,M. De Buyzere,Sofie Bekaert,Patrick Segers,Dirk De Bacquer,G. De Backer,Thierry C. Gillebert,JM Kaufman +8 more
TL;DR: The study suggests an opposite link, albeit modestly, of testosterone and oestradiol with left ventricle systolic function in healthy middle-aged men, which provides a partial explanation for the overall neutral effect on CVD of testosterone.
Journal ArticleDOI
Addition of a novel, protective family history category allows better profiling of cardiovascular risk and atherosclerotic burden in the general population. The Asklepios Study.
Caroline M. Van daele,Tim De Meyer,Marc De Buyzere,Thierry C. Gillebert,Simon Denil,Sofie Bekaert,Julio A. Chirinos,Patrick Segers,Guy De Backer,Dirk De Bacquer,Ernst Rietzschel,Ernst Rietzschel +11 more
TL;DR: A novel, extended FH definition is superior to the conventional definition in profiling cardiovascular risk and atherosclerotic burden in the general population and remained a significant predictor of subclinical atherosclerosis after adjusting for confounders.