S
Solenn Kermarrec
Researcher at University of Rennes
Publications - 20
Citations - 984
Solenn Kermarrec is an academic researcher from University of Rennes. The author has contributed to research in topics: Autism & Cognition. The author has an hindex of 10, co-authored 20 publications receiving 796 citations. Previous affiliations of Solenn Kermarrec include Paris Descartes University & Centre national de la recherche scientifique.
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Journal ArticleDOI
Gene × Environment interactions in autism spectrum disorders: role of epigenetic mechanisms.
Sylvie Tordjman,Sylvie Tordjman,Eszter Somogyi,Nathalie Coulon,Solenn Kermarrec,Solenn Kermarrec,David Cohen,Guillaume Bronsard,Olivier Bonnot,Catherine Weismann-Arcache,Michel Botbol,Michel Botbol,Bertrand Lauth,Vincent Ginchat,Pierre L. Roubertoux,Marianne Barbu-Roth,Viviane Kovess,Marie-Maude Geoffray,Jean Xavier +18 more
TL;DR: Arguments for a genetic contribution to autism, based on updated family and twin studies, are examined and the possible role of epigenetic mechanisms reported in genetic disorders associated with ASD is discussed.
Journal ArticleDOI
Autism as a Disorder of Biological and Behavioral Rhythms: Toward New Therapeutic Perspectives
Sylvie Tordjman,Sylvie Tordjman,Katherine S. Davlantis,Nicolas Georgieff,Marie-Maude Geoffray,Mario Speranza,George M. Anderson,Jean Xavier,Michel Botbol,Michel Botbol,Cécile Oriol,Eric Bellissant,Eric Bellissant,Julie Vernay-Leconte,Claire Fougerou,Claire Fougerou,Anne Hespel,Anne Hespel,Aude Tavenard,Aude Tavenard,David Cohen,Solenn Kermarrec,Solenn Kermarrec,Nathalie Coulon,Olivier Bonnot,Geraldine Dawson +25 more
TL;DR: The hypothesis is developed that an integrated approach focusing on biological, motor, emotional, and interpersonal rhythms may open interesting therapeutic perspectives for children with autism.
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Advances in the research of melatonin in autism spectrum disorders: literature review and new perspectives.
Sylvie Tordjman,Imen Najjar,Eric Bellissant,George M. Anderson,Marianne Barbu-Roth,David Cohen,Nemat Jaafari,Olivier Schischmanoff,Remi Fagard,Enas Lagdas,Solenn Kermarrec,Sophie Ribardiere,Michel Botbol,Claire Fougerou,Guillaume Bronsard,Julie Vernay-Leconte +15 more
TL;DR: It is emphasized that randomized clinical trials in autism spectrum disorders are warranted to establish potential therapeutic efficacy of melatonin for social communication impairments and stereotyped behaviors or interests.
Journal ArticleDOI
Day and nighttime excretion of 6-sulphatoxymelatonin in adolescents and young adults with autistic disorder
Sylvie Tordjman,George M. Anderson,Eric Bellissant,Michel Botbol,Henriette Charbuy,Françoise Camus,Rozenn Graignic,Solenn Kermarrec,Claire Fougerou,David Cohen,Yvan Touitou +10 more
TL;DR: A deficit in melatonin production is present both at daytime and at nighttime in individuals with autism, particularly in the most severely affected individuals, and interest in potential therapeutic uses of melatonin in autistic disorder is highlighted.
Journal ArticleDOI
Altered circadian patterns of salivary cortisol in low-functioning children and adolescents with autism.
Sylvie Tordjman,Sylvie Tordjman,George M. Anderson,Solenn Kermarrec,Solenn Kermarrec,Olivier Bonnot,Marie-Maude Geoffray,Sylvie Brailly-Tabard,Amel Chaouch,Isabelle Colliot,Séverine Trabado,Guillaume Bronsard,Nathalie Coulon,Michel Botbol,Henriette Charbuy,Françoise Camus,Yvan Touitou +16 more
TL;DR: The elevated salivary cortisol levels observed in autism over the 24-h period in a repeated stressful condition, flattened diurnal cortisol patterns and the apparent effect of anticipation are consistent with prior findings in high trait anxiety.