S
Sonal V Bhujbal
Researcher at Purdue University
Publications - 12
Citations - 358
Sonal V Bhujbal is an academic researcher from Purdue University. The author has contributed to research in topics: Spray drying & Aerosolization. The author has an hindex of 7, co-authored 10 publications receiving 134 citations. Previous affiliations of Sonal V Bhujbal include Creighton University.
Papers
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Journal ArticleDOI
Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies.
Sonal V Bhujbal,Biplob Mitra,Uday Jain,Yuchuan Gong,Anjali Agrawal,Shyam Karki,Lynne S. Taylor,Sumit Kumar,Qi Tony Zhou +8 more
TL;DR: This review provides an updated overview of manufacturing techniques for preparing ASDs, and selection strategies are proposed to identify suitable manufacturing methods, which may aid in the development of ASDs with satisfactory physical stability.
Journal ArticleDOI
Influence of excipients on physical and aerosolization stability of spray dried high-dose powder formulations for inhalation
TL;DR: In this article, the authors investigated the influence of excipients on physical and aerosolization stability of spray-dried Ciprofloxacin dry powder inhaler formulations.
Journal ArticleDOI
Improved Physical Stability and Aerosolization of Inhalable Amorphous Ciprofloxacin Powder Formulations by Incorporating Synergistic Colistin.
Nivedita Shetty,Patricia Ahn,Hee Jun Park,Sonal V Bhujbal,Dmitry Zemlyanov,Alex Cavallaro,Sharad Mangal,Jian Li,Qi Tony Zhou +8 more
TL;DR: It is demonstrated that incorporation of colistin in the spray-dried formulations can improve physical stability and aerosolization of amorphous ciprofloxacin at 55% RH and prevent particle fusion and deterioration in aerosol performance.
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Amorphous solid dispersion formation via solvent granulation - A case study with ritonavir and lopinavir.
TL;DR: In this article, solvent granulation was used to make amorphous solid dispersion (ASD) of two anti-HIV drugs, ritonavir and lopinavir.
Journal ArticleDOI
Qualitative and Quantitative Characterization of Composition Heterogeneity on the Surface of Spray Dried Amorphous Solid Dispersion Particles by an Advanced Surface Analysis Platform with High Surface Sensitivity and Superior Spatial Resolution.
TL;DR: An advanced surface characterization platform consisting of two complementary techniques: X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS) is presented that could differentiate two batches of spray dried ASD particles with a subtle difference in surface composition produced by varying feed solution solvents.