Biplob Mitra

TL;DR: This review provides an updated overview of manufacturing techniques for preparing ASDs, and selection strategies are proposed to identify suitable manufacturing methods, which may aid in the development of ASDs with satisfactory physical stability.

TL;DR: This work demonstrated drug substance particle size and concentration ranges that achieve acceptable mini- tablet quality attributes for use as a single or composite dosage unit and supported the manufacturing feasibility of quality mini-tablets, and their applicability as a flexible drug delivery tool.

TL;DR: In this article, a platform formulation with 60, 80, and 100 µm (particle size D6,3) ibuprofen at 3, 14, and 25% loadings were directly compressed into 1.2, 1.5, 2, and 2.5 µm diameter mini-tablets.

TL;DR: This study provides a framework for developing low dose micro-tablets with acceptable quality attributes using HSWG process for micro-dosing, enhanced dose flexibility, and decreased excipient burden.

TL;DR: A workshop on pediatric formulation development was organized by the University of Maryland's Center of Excellence in Regulatory Science and Innovation (M-CERSI), the U.S. Food and Drug Administration (FDA) and the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Drug Product Pediatric Working Group (PWG) as mentioned in this paper.