Sumit Kumar

TL;DR: This review provides an updated overview of manufacturing techniques for preparing ASDs, and selection strategies are proposed to identify suitable manufacturing methods, which may aid in the development of ASDs with satisfactory physical stability.

TL;DR: The work illustrated the potential application of FDM technology in the development of oral fixed dose combination for personalized clinical treatment by minimizing the degradation of RFC in the acidic condition and potentially avoid drug-drug interaction.

TL;DR: In this paper, a range of plain and drug loaded polymers were investigated and assessed for their printability in comparison to commercial filaments and principal component analysis was used to compare the printability of the polymer and to identify the contribution of each mechanical property.

TL;DR: To evaluate the effect of wetting agents and disintegrants on the dissolution performance of dried nanocrystals of an active pharmaceutical ingredient (API) with poor wetting property, Danazol, a BCS Class II compound with high LogP and low polar surface area, was chosen as a model compound.

TL;DR: In this article, a novel use of nanocrystalline suspension combined with high shear wet granulation for the first time was presented, which resulted in excellent content uniformity among individual micro-tablets even at a dose strength as low as 0.16 mcg, whereas micronized drug resulted in unacceptable CU even at 5x higher dose strength (0.8 mcg).