S
Sonia Vivet
Researcher at University of Paris-Sud
Publications - 10
Citations - 750
Sonia Vivet is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Apoptosis & Mitosis. The author has an hindex of 9, co-authored 10 publications receiving 703 citations. Previous affiliations of Sonia Vivet include Institut Gustave Roussy & French Institute of Health and Medical Research.
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Journal ArticleDOI
Apoptosis regulation in tetraploid cancer cells
Maria Castedo,Arnaud Coquelle,Sonia Vivet,Ilio Vitale,Audrey Kauffmann,Philippe Dessen,Marie O. Pequignot,Noelia Casares,A. Valent,Shahul Mouhamad,Elise Schmitt,Nazanine Modjtahedi,William Vainchenker,Laurence Zitvogel,Vladimir Lazar,Carmen Garrido,Guido Kroemer +16 more
TL;DR: Tetraploid cells exhibited an enhanced rate of spontaneous apoptosis that could be suppressed by inhibition of p53 or by knockdown of proapoptotic p53 target genes such as BBC3/Puma, GADD45A and ferredoxin reductase.
Journal ArticleDOI
Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos
Ilio Vitale,Laura Senovilla,Laura Senovilla,Laura Senovilla,Mohamed Jemaà,Mohamed Jemaà,Mohamed Jemaà,Mickaël Michaud,Mickaël Michaud,Mickaël Michaud,Lorenzo Galluzzi,Lorenzo Galluzzi,Lorenzo Galluzzi,Oliver Kepp,Oliver Kepp,Oliver Kepp,Lisa Nanty,Lisa Nanty,Lisa Nanty,Alfredo Criollo,Alfredo Criollo,Alfredo Criollo,Santiago Rello-Varona,Santiago Rello-Varona,Santiago Rello-Varona,Gwenola Manic,Gwenola Manic,Gwenola Manic,Didier Métivier,Didier Métivier,Didier Métivier,Sonia Vivet,Sonia Vivet,Sonia Vivet,Nicolas Tajeddine,Nicolas Tajeddine,Nicolas Tajeddine,Nicholas Joza,Nicholas Joza,Nicholas Joza,Alexander Valent,Maria Castedo,Maria Castedo,Maria Castedo,Guido Kroemer,Guido Kroemer,Guido Kroemer +46 more
TL;DR: The results elucidate the mechanisms through which asymmetric cell division drives chromosomal instability in tetraploid cells and prevent multipolar mitoses and exerts genome‐stabilizing effects.
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Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone
Jens Hoffmann,Ilio Vitale,Ilio Vitale,Bernd Buchmann,Lorenzo Galluzzi,Lorenzo Galluzzi,Wolfgang Schwede,Laura Senovilla,Laura Senovilla,Werner Skuballa,Sonia Vivet,Sonia Vivet,Rosemarie B. Lichtner,Jose Miguel Vicencio,Jose Miguel Vicencio,Theocharis Panaretakis,Gerhard Siemeister,Hermann Lage,Lisa Nanty,Lisa Nanty,Stefanie Hammer,Kevin Mittelstaedt,Sebastian Winsel,Sebastian Winsel,Julia Eschenbrenner,Julia Eschenbrenner,Maria Castedo,Maria Castedo,Carine Demarche,Ulrich Klar,Guido Kroemer,Guido Kroemer +31 more
TL;DR: Sagopilone is highly effective in reducing the growth of paclitaxel-resistant cancer cells and is more cytotoxic than other epothilones in a large panel of human cancer cell lines in vitro and in vivo.
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Hafnium oxide nanoparticles: toward an in vitro predictive biological effect?
Julie Marill,Naeemunnisa Mohamed Anesary,Ping Zhang,Sonia Vivet,Elsa Borghi,Laurent Levy,Agnès Pottier +6 more
TL;DR: Preliminary results suggest a predictable in vitro biological effect of NBTXR3 nanoparticles exposed to ionizing radiation.
Journal ArticleDOI
Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway
Ilio Vitale,Ilio Vitale,Ilio Vitale,Lorenzo Galluzzi,Lorenzo Galluzzi,Lorenzo Galluzzi,Sonia Vivet,Sonia Vivet,Sonia Vivet,Lisa Nanty,Lisa Nanty,Philippe Dessen,Laura Senovilla,Laura Senovilla,Laura Senovilla,Ken A. Olaussen,Ken A. Olaussen,Ken A. Olaussen,Vladimir Lazar,M. Prudhomme,Roy M. Golsteyn,Maria Castedo,Maria Castedo,Maria Castedo,Guido Kroemer,Guido Kroemer,Guido Kroemer +26 more
TL;DR: It is demonstrated that, in tetraploid tumor cells, the inhibition of Chk1 sequentially triggers aberrant mitosis, p53 activation and Puma/BBC3-dependent mitochondrial apoptosis.