S
Soon Young Shin
Researcher at Konkuk University
Publications - 197
Citations - 4567
Soon Young Shin is an academic researcher from Konkuk University. The author has contributed to research in topics: Apoptosis & MAPK/ERK pathway. The author has an hindex of 35, co-authored 182 publications receiving 3980 citations. Previous affiliations of Soon Young Shin include Korea Research Institute of Bioscience and Biotechnology & Hanyang University.
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Formation and Removal of α-Synuclein Aggregates in Cells Exposed to Mitochondrial Inhibitors
TL;DR: Results suggest that the formation of α-synuclein inclusions could be initiated by an impaired mitochondrial function and be reversed by restoring normal mitochondrial metabolism, and partially inhibited by proteasome inhibitors.
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Biological Imaging of HEK293 Cells Expressing PLCγ1 Using Surface-Enhanced Raman Microscopy
Sangyeop Lee,Sungyong Kim,Jaebum Choo,Soon Young Shin,Young Han Lee,Ha Young Choi,Seunghan Ha,Kyungho Kang,Chil Hwan Oh +8 more
TL;DR: The results demonstrate the potential feasibility of SERS imaging technology for the highly sensitive imaging of cancer biomarkers in live cells and develop the procedures to label live cells with bimetallic nanoprobes.
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Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway.
TL;DR: It is demonstrated that curcumin down-regulates P- gp expression in multidrug-resistant L1210/Adr cells and can contribute to the reversal of the MDR phenotype, probably due to the suppression of P-gp expression via the inhibition of the PI3K/Akt/NF-kappa B signaling pathway.
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Surface-enhanced Raman scattering imaging of HER2 cancer markers overexpressed in single MCF7 cells using antibody conjugated hollow gold nanospheres.
Sangyeop Lee,Hyangah Chon,Moonkwon Lee,Jaebum Choo,Soon Young Shin,Young Han Lee,Im Joo Rhyu,Sang Wook Son,Chil Hwan Oh +8 more
TL;DR: The results demonstrate the potential feasibility of HGNs as highly sensitive and homogeneous sensing probes for biological imaging of cancer markers in live cells.
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SERS imaging of HER2-overexpressed MCF7 cells using antibody-conjugated gold nanorods
Hyejin Park,Sangyeop Lee,Lingxin Chen,Eun Kyu Lee,Soon Young Shin,Young Han Lee,Sang Wook Son,Chil Hwan Oh,Joon Myong Song,Seong Ho Kang,Jaebum Choo +10 more
TL;DR: The experimental results demonstrate the potential feasibility of antibody-conjugated GNRs for the highly sensitive targeting and imaging of biomarkers expressed on the surface membrane of cancer cells.