S
Sophie J. Bakri
Researcher at Mayo Clinic
Publications - 194
Citations - 7526
Sophie J. Bakri is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Macular degeneration & Visual acuity. The author has an hindex of 41, co-authored 178 publications receiving 6660 citations. Previous affiliations of Sophie J. Bakri include Cleveland Clinic & Albany Medical College.
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Journal ArticleDOI
Pharmacokinetics of Intravitreal Bevacizumab (Avastin)
TL;DR: The vitreous half-life of 1.25 mg intravitreal bevacizumab (Avastin) is 4.32 days in a rabbit eye, compared with 4.88 days and 6.86 days for the aqueous and serum values, respectively.
Journal ArticleDOI
Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection
TL;DR: Because triamcinolone pharmacokinetics were characterized only in elderly patients with macular edema, the results cannot be extrapolated to other patient populations.
Journal ArticleDOI
Pharmacokinetics of intravitreal ranibizumab (Lucentis).
TL;DR: Although vitreous concentrations of ranibizumab declined in a monoexponential fashion with a half-life of 2.88 days, concentrations of >0.1 microg/ml ranibzumab were maintained in the Vitreous humor for 29 days, whereas small amounts of intravitreal bevacizumAB have been detected in the serum and fellow uninjected eye.
Journal ArticleDOI
Acute endophthalmitis following intravitreal triamcinolone acetonide injection
Darius M. Moshfeghi,Peter K. Kaiser,Ingrid U. Scott,Jonathan E. Sears,Matthew S. Benz,Juan P. Sinesterra,Richard S. Kaiser,Sophie J. Bakri,Raj K. Maturi,Jonathan B. Belmont,Paul M. Beer,Timothy G. Murray,Hugo Quiroz-Mercado,William F. Mieler +13 more
TL;DR: In this paper, the authors report the clinical features, causative organisms, management, and visual acuity outcomes of eight eyes of eight patients who developed acute postoperative endophthalmitis following intravitreal injection of triamcinolone acetonide (IVTA).
Journal ArticleDOI
Intravitreal Injection Technique and Monitoring: Updated Guidelines of an Expert Panel
Robert L. Avery,Sophie J. Bakri,Mark S. Blumenkranz,Alexander J. Brucker,Emmett T. Cunningham,Donald J DʼAmico,Pravin U. Dugel,Harry W. Flynn,K. Bailey Freund,Julia A Haller,J. Michael Jumper,Jeffrey M Liebmann,Colin A. McCannel,William F. Mieler,Christopher N. Ta,George A. Williams +15 more
TL;DR: New guidelines on IVT injection technique and monitoring are proposed based on a review of published literature and expert panel deliberations and emphasized the continued importance of applying povidone–iodine to and avoiding eyelid contact with the intended injection site and needle.