S
Sophie Van Linthout
Researcher at Humboldt University of Berlin
Publications - 38
Citations - 2075
Sophie Van Linthout is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Myocarditis & Heart failure. The author has an hindex of 21, co-authored 38 publications receiving 1338 citations. Previous affiliations of Sophie Van Linthout include Charité & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Myocarditis and inflammatory cardiomyopathy: current evidence and future directions.
Carsten Tschöpe,Enrico Ammirati,Biykem Bozkurt,Biykem Bozkurt,Alida L.P. Caforio,Leslie T. Cooper,Stephan B. Felix,Joshua M. Hare,Bettina Heidecker,Stephane Heymans,Stephane Heymans,Norbert Hubner,Sebastian Kelle,Karin Klingel,Henrike Maatz,Abdul Shokor Parwani,Frank Spillmann,Randall C. Starling,Hiroyuki Tsutsui,Petar M. Seferovic,Sophie Van Linthout +20 more
TL;DR: Improved standardization of available invasive and noninvasive diagnostic tools and a consensus on their specific use are needed to allow specific diagnosis and stratification of patient cohorts for the implementation of aetiology-based therapies.
Journal ArticleDOI
Inflammation – Cause or Consequence of Heart Failure or Both?
TL;DR: The diversity of inflammation addresses the need for a tailored characterization of inflammation enabling differentiation of inflammation and subsequent target-specific strategies and points out the need to control the inflammatory process at an early stage avoiding chronic inflammation and heart failure.
Journal ArticleDOI
Management of Myocarditis-Related Cardiomyopathy in Adults
Carsten Tschöpe,Leslie T. Cooper,Guillermo Torre-Amione,Guillermo Torre-Amione,Sophie Van Linthout +4 more
TL;DR: Recent advances in translational research that influence the utility of endomyocardial biopsy for the management of inflammatory cardiomyopathies are summarized and emerging therapies for myocarditis based on mechanistic hypotheses are entering clinical trials.
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Cardioprotective and Anti-Inflammatory Effects of Interleukin Converting Enzyme Inhibition in Experimental Diabetic Cardiomyopathy
Dirk Westermann,Sophie Van Linthout,Sameer Dhayat,Nasser A. Dhayat,Felicitas Escher,Carola Bucker-Gartner,Frank Spillmann,Michel Noutsias,Alexander Riad,Heinz-Peter Schultheiss,Carsten Tschöpe +10 more
TL;DR: Cardiac dysfunction is associated with cardiac inflammation in experimental diabetic cardiomyopathy and both of these—cardiac dysfunction and inflammation—are attenuated after treatment with ICEI, suggesting that anticytokine-based therapies might be beneficial in diabetic carduomyopathy.
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Human ApoA-I Transfer Attenuates Transplant Arteriosclerosis via Enhanced Incorporation of Bone marrow–derived Endothelial Progenitor Cells
Yingmei Feng,Frank Jacobs,Eline Van Craeyveld,Christine Brunaud,Jan Snoeys,Marc Tjwa,Sophie Van Linthout,Bart De Geest +7 more
TL;DR: Human apoA-I transfer increases the number of circulating EPCs, enhances their incorporation into allografts, promotes endothelial regeneration, and attenuates neointima formation in a murine model of transplant arteriosclerosis.