S
Sospeter Ngoci Njeru
Researcher at RMIT University
Publications - 17
Citations - 236
Sospeter Ngoci Njeru is an academic researcher from RMIT University. The author has contributed to research in topics: Antimicrobial & Anopheles gambiae. The author has an hindex of 7, co-authored 15 publications receiving 154 citations. Previous affiliations of Sospeter Ngoci Njeru include Paul Ehrlich Institute & National Institutes of Health.
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Journal ArticleDOI
Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation.
Zhiyang Chen,Amro Elias,Friedrich Becker,Martin Hölzer,Seyed Mohammad Mahdi Rasa,Sospeter Ngoci Njeru,Bing Han,Simone Di Sanzo,Yulin Chen,Duozhuang Tang,Si Tao,Ronny Haenold,Ronny Haenold,Marco Groth,Vasily S. Romanov,Joanna Kirkpatrick,Johann M. Kraus,Hans A. Kestler,Manja Marz,Manja Marz,Alessandro Ori,Francesco Neri,Yohei Morita,K. Lenhard Rudolph,K. Lenhard Rudolph +24 more
TL;DR: It is shown that aged hematopoietic stem and progenitor cells (HSPCs) exhibit increased ground‐stage NF‐&kgr;B activity, which enhances their responsiveness to undergo differentiation and loss of self‐renewal in response to inflammation.
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Prospects for malaria control through manipulation of mosquito larval habitats and olfactory-mediated behavioural responses using plant-derived compounds
Jackson M. Muema,Joel L. Bargul,Joel L. Bargul,Sospeter Ngoci Njeru,Joab O. Onyango,Susan S Imbahale +5 more
TL;DR: The combination of push-pull methods and larval control have the potential to reduce malaria vector populations, thus minimising the risk of contracting malaria especially in resource-constrained communities where access to synthetic insecticides is a challenge.
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Antimicrobial and cytotoxicity properties of the crude extracts and fractions of Premna resinosa (Hochst.) Schauer (Compositae): Kenyan traditional medicinal plant
TL;DR: Premna resinosa has high selective potential as a source of novel lead for antituberculous, antibacterial and antifungal drugs, of particular relevance is high activity against MRSA, S. aureus, C. albicans and MTB which are great public health challenge due to drug resistance development and as major sources of community and hospital based infections.
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Potential of Camellia sinensis proanthocyanidins-rich fraction for controlling malaria mosquito populations through disruption of larval development.
Jackson M. Muema,Joel L. Bargul,Joel L. Bargul,Steven G. Nyanjom,James M. Mutunga,Sospeter Ngoci Njeru +5 more
TL;DR: The findings demonstrate the potential of green tea extract and its active constituents in disrupting mosquito larval development and could contribute to the control of mosquito populations and improved management of malaria.
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Methanolic extract of Agerantum conyzoides exhibited toxicity and growth disruption activities against Anopheles gambiae sensu stricto and Anopheles arabiensis larvae
TL;DR: The extract displayed considerable larvicidal activity and inhibited emergence of adult mosquitoes relative to experimental controls, a phenomenon probably associated with induced developmental hormone imbalance.