S
Soumen Roy
Researcher at National Institutes of Health
Publications - 18
Citations - 2260
Soumen Roy is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Hair cell & Ototoxicity. The author has an hindex of 15, co-authored 18 publications receiving 1519 citations. Previous affiliations of Soumen Roy include University of Innsbruck & Innsbruck Medical University.
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Journal ArticleDOI
Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells
Chi Ma,Miaojun Han,Bernd Heinrich,Qiong Fu,Qianfei Zhang,Milan Sandhu,David Agdashian,Masaki Terabe,Jay A. Berzofsky,Valerie Fako,Thomas Ritz,Thomas Longerich,Thomas Longerich,Casey M. Theriot,John A. McCulloch,Soumen Roy,Wuxing Yuan,Vishal Thovarai,Shurjo K. Sen,Mathuros Ruchirawat,Firouzeh Korangy,Xin Wei Wang,Giorgio Trinchieri,Tim F. Greten +23 more
TL;DR: The role of bile acids in immunosurveillance of tumors growing in the liver is focused on and altering commensal gut bacteria induced a liver-selective antitumor effect.
Journal ArticleDOI
Microbiota: a key orchestrator of cancer therapy.
Soumen Roy,Giorgio Trinchieri +1 more
TL;DR: The evidence for the ability of the microbiota to modulate chemotherapy, radiotherapy and immunotherapy is discussed with a focus on the microbial species involved, their mechanism of action and the possibility of targeting the microbiome to improve anticancer efficacy while preventing toxicity.
Journal ArticleDOI
Microbes and Cancer
Amiran Dzutsev,Jonathan H. Badger,Ernesto Perez-Chanona,Soumen Roy,Rosalba Salcedo,Carolyne K. Smith,Giorgio Trinchieri +6 more
TL;DR: The mechanisms underlying the interaction of the microbiota with cancer and the evidence suggesting that the microbiota could be targeted to improve therapy while attenuating adverse reactions are reviewed.
Journal ArticleDOI
Inner ear supporting cells protect hair cells by secreting HSP70
Lindsey A. May,Inga I. Kramarenko,Carlene Brandon,Christina Voelkel-Johnson,Soumen Roy,Kristy Truong,Shimon P. Francis,Elyssa L. Monzack,Fu-Shing Lee,Lisa L. Cunningham +9 more
TL;DR: The data indicate that supporting cells mediate the protective effect of HSP70 against hair cell death, and they suggest a major role for supporting cells in determining the fate of hair cells exposed to stress.
Journal ArticleDOI
Cell-specific targeting in the mouse inner ear using nanoparticles conjugated with a neurotrophin-derived peptide ligand: potential tool for drug delivery.
Soumen Roy,A.H. Johnston,Tracey A. Newman,Rudolf Glueckert,Jozsef Dudas,Mario Bitsche,Elisa Corbacella,Gunde Rieger,Alessandro Martini,Anneliese Schrott-Fischer +9 more
TL;DR: The results indicate a selective cochlear cell targeting by MFNPs, which may be a potential tool for cell specific drug and gene delivery to the inner ear.