Soumya Swaminathan

TL;DR: Drug resistance including MDR-TB was observed in a significant proportion of extrapulmonary specimens referred for DST, and guidelines for M DR-TB management should have explicit sections on extra-pulmonary tuberculosis and training on laboratory techniques is urgently required.

TL;DR: An international expert panel convened by the US National Institutes of Health identified high-priority research areas during pregnancy, including preventing progression of latent tuberculosis infection, especially in women coinfected with human immunodeficiency virus and evaluating new agents/regimens for treatment of multidrug-resistant tuberculosis.

TL;DR: The expected results include greater global clinical research capacity in high-burden settings, and increased local access to quality data and specimens for members of each network and their domestic and international collaborators.

TL;DR: Artificial intelligence algorithms confirmed that pyrazinamide was not predictive of good clinical outcomes in children ≤ 6 years who had extrapulmonary tuberculosis, so adding a drug that works inside macrophages could benefit children with disseminated tuberculosis.

TL;DR: Xpert MTB/RIF with advantages of quick turnaround testing-time, high proportion of interpretable results and feasibility of rapid rollout, substantially improved the diagnosis of bacteriologically confirmed TB in children, while simultaneously detecting rifampicin resistance.