S
Srivari Chandrasekhar
Researcher at Indian Institute of Chemical Technology
Publications - 461
Citations - 8395
Srivari Chandrasekhar is an academic researcher from Indian Institute of Chemical Technology. The author has contributed to research in topics: Catalysis & Total synthesis. The author has an hindex of 42, co-authored 453 publications receiving 7798 citations. Previous affiliations of Srivari Chandrasekhar include Academy of Scientific and Innovative Research & University of Texas Southwestern Medical Center.
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Design, synthesis and cytotoxic studies on the simplified oxy analog of eleutherobin☆
Srivari Chandrasekhar,V. Jagadeshwar,Ch. Narsihmulu,M. Sarangapani,D. R. Krishna,J. Vidyasagar,Dolly Vijay,G. Narahari Sastry +7 more
TL;DR: A straight forward entry into nine membered B ring of eleutherobin as oxy analog and its cyctotoxic properties on HBL cell lines is described.
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Expanding Diversity without Protecting Groups: (+)-Sclareolide to Indolosesquiterpene Alkaloid Mycoleptodiscin A and Analogues.
TL;DR: Short and scalable synthesis of the complex pentacyclic indolosesquiterpene natural product mycoleptodiscin A has been achieved from commercially available diterpenoid (+)-sclareolide in 19% overall yield.
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The Ireland–Claisen rearrangement strategy towards the synthesis of the schizophrenia drug, (+)-asenapine
Raghunath Reddy Anugu,Raghunath Reddy Anugu,Prathama S. Mainkar,Balasubramanian Sridhar,Srivari Chandrasekhar,Srivari Chandrasekhar +5 more
TL;DR: (±)-Asenapine, sold in the market as Saphris/Sycrest for the treatment of bipolar disorders, is synthesized in an optically pure form involving an Ireland-Claisen rearrangement as the key step, which allows access to all diastereomers.
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Methylenephenylsulfone appended acetals and ketals: New class of carbonyl protective groups cleavable by DBU
TL;DR: In this paper, 1,8-diazabicyclo[5.4.0]-7-undecene (DBU) was used to remove 1.3-phenylsulfonyl 1,2 propane diol.
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Total synthesis of 6-epiprelactone-V via a syn-selective oxygen tethered intramolecular Michael reaction☆
TL;DR: The intramolecular protective group assisted syn-1,3-diol synthesis has been efficiently utilized in a short synthesis of 6-epiprelactone-V starting from (S)-malic acid.