Stan Z. Gertler

TL;DR: Ca2+ fluxes through ω-conopeptide-sensitive N-type Ca2+ channels are critically involved in the pathogenesis of selective neuronal death up to 24 h after ischemia in the hippocampus and that this conopeptid protection extends, even when given late, to neocortical infarct reduction.

TL;DR: Trastuzumab treatment beyond progression appears to be of value, producing responses and clinical benefit, and is well tolerated without significant cardiac toxicity, and the feasibility of this approach warrants examination in prospective trials.

TL;DR: In this paper, the authors evaluated preferences associated with grade I/II and grade III/IV chemotherapy side effects among breast cancer patients receiving chemotherapy and assessed trade-offs that patients are willing to make between treatment side effects and the route and schedule of treatment administration.

TL;DR: High dose nitro-arginine caused an increase in hypertension in the spontaneously hypertensive rats and increased the severity of focal ischemia as measured by intra-ischemic regional cerebral blood flows.

TL;DR: The observation that SF remained stable across time is encouraging news, however, longer follow-up and the inclusion of women who were premenopausal at diagnosis are needed to determine the potential influence of extended duration of ET on SD.