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Alastair M. Buchan

Researcher at University of Oxford

Publications -  362
Citations -  31930

Alastair M. Buchan is an academic researcher from University of Oxford. The author has contributed to research in topics: Stroke & Ischemia. The author has an hindex of 79, co-authored 350 publications receiving 29036 citations. Previous affiliations of Alastair M. Buchan include University of Calgary & National Research Council.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Glial and neuronal control of brain blood flow.

David Attwell, +5 more
- 11 Nov 2010 - 
TL;DR: It is now recognized that neurotransmitter-mediated signalling has a key role in regulating cerebral blood flow, that much of this control is mediated by astrocytes, that oxygen modulates blood flow regulation, and that blood flow may be controlled by capillaries as well as by arterioles.
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Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy

Philip A. Barber, +4 more
- 13 May 2000 - 
TL;DR: This CT score is simple and reliable and identifies stroke patients unlikely to make an independent recovery despite thrombolytic treatment as well as primary outcomes, including symptomatic intracerebral haemorrhage and 3-month functional outcome.
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Capillary pericytes regulate cerebral blood flow in health and disease

Catherine N. Hall, +9 more
- 03 Apr 2014 - 
TL;DR: It is demonstrated that neuronal activity and the neurotransmitter glutamate evoke the release of messengers that dilate capillaries by actively relaxing pericytes, which are major regulators of cerebral blood flow and initiators of functional imaging signals.
Journal Article

Use of the Alberta Stroke Program Early CT Score (ASPECTS) for Assessing CT Scans in Patients with Acute Stroke

J. H. Warwick Pexman, +7 more
- 01 Sep 2001 - 
TL;DR: ASPECTS is a systematic, robust, and practical method that can be applied to different axial baselines and clinician agreement is superior to that of the 1/3 MCA rule.