In this paper we report the set-up and results of the Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) organized in conjunction with the MICCAI 2012 and 2013 conferences Twenty state-of-the-art tumor segmentation algorithms were applied to a set of 65 multi-contrast MR scans of low- and high-grade glioma patients—manually annotated by up to four raters—and to 65 comparable scans generated using tumor image simulation software Quantitative evaluations revealed considerable disagreement between the human raters in segmenting various tumor sub-regions (Dice scores in the range 74%–85%), illustrating the difficulty of this task We found that different algorithms worked best for different sub-regions (reaching performance comparable to human inter-rater variability), but that no single algorithm ranked in the top for all sub-regions simultaneously Fusing several good algorithms using a hierarchical majority vote yielded segmentations that consistently ranked above all individual algorithms, indicating remaining opportunities for further methodological improvements The BRATS image data and manual annotations continue to be publicly available through an online evaluation system as an ongoing benchmarking resource

/pdf/the-multimodal-brain-tumor-image-segmentation-benchmark-2gfraj98dk.pdf

The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)

Due to the fast inference and good performance, discriminative learning methods have been widely studied in image denoising. However, these methods mostly learn a specific model for each noise level, and require multiple models for denoising images with different noise levels. They also lack flexibility to deal with spatially variant noise, limiting their applications in practical denoising. To address these issues, we present a fast and flexible denoising convolutional neural network, namely FFDNet, with a tunable noise level map as the input. The proposed FFDNet works on downsampled sub-images, achieving a good trade-off between inference speed and denoising performance. In contrast to the existing discriminative denoisers, FFDNet enjoys several desirable properties, including: 1) the ability to handle a wide range of noise levels (i.e., [0, 75]) effectively with a single network; 2) the ability to remove spatially variant noise by specifying a non-uniform noise level map; and 3) faster speed than benchmark BM3D even on CPU without sacrificing denoising performance. Extensive experiments on synthetic and real noisy images are conducted to evaluate FFDNet in comparison with state-of-the-art denoisers. The results show that FFDNet is effective and efficient, making it highly attractive for practical denoising applications.

FFDNet: Toward a Fast and Flexible Solution for CNN-Based Image Denoising

When one captures images in low-light conditions, the images often suffer from low visibility. Besides degrading the visual aesthetics of images, this poor quality may also significantly degenerate the performance of many computer vision and multimedia algorithms that are primarily designed for high-quality inputs. In this paper, we propose a simple yet effective low-light image enhancement (LIME) method. More concretely, the illumination of each pixel is first estimated individually by finding the maximum value in R, G, and B channels. Furthermore, we refine the initial illumination map by imposing a structure prior on it, as the final illumination map. Having the well-constructed illumination map, the enhancement can be achieved accordingly. Experiments on a number of challenging low-light images are present to reveal the efficacy of our LIME and show its superiority over several state-of-the-arts in terms of enhancement quality and efficiency.

https://ieeexplore.ieee.org/ielaam/83/7763897/7782813-aam.pdf

LIME: Low-Light Image Enhancement via Illumination Map Estimation

Course Description This is an advanced course in which we explore the field of Statistical Optics. Topics covered include such subjects as the statistical properties of natural (thermal) and laser light, spatial and temporal coherence, effects of partial coherence on optical imaging instruments, effects on imaging due to randomly inhomogeneous media, and a statistical treatment of the detection of light. Development of this more comprehensive model of the behavior of light draws upon the use of tools traditionally available to the electrical engineer, such as linear system theory and the theory of stochastic processes.

http://ieeexplore.ieee.org/iel5/3/23094/01073023.pdf

Statistical optics

tions. Bootstrap has found many applications in engineering field, including artificial neural networks, biomedical engineering, environmental engineering, image processing, and radar and sonar signal processing. Basic concepts of the bootstrap are summarized in each section as a step-by-step algorithm for ease of implementation. Most of the applications are taken from the signal processing literature. The principles of the bootstrap are introduced in Chapter 2. Both the nonparametric and parametric bootstrap procedures are explained. Babu and Singh (1984) have demonstrated that in general, these two procedures behave similarly for pivotal (Studentized) statistics. The fact that the bootstrap is not the solution for all of the problems has been known to statistics community for a long time; however, this fact is rarely touched on in the manuscripts meant for practitioners. It was first observed by Babu (1984) that the bootstrap does not work in the infinite variance case. Bootstrap Techniques for Signal Processing explains the limitations of bootstrap method with an example. I especially liked the presentation style. The basic results are stated without proofs; however, the application of each result is presented as a simple step-by-step process, easy for nonstatisticians to follow. The bootstrap procedures, such as moving block bootstrap for dependent data, along with applications to autoregressive models and for estimation of power spectral density, are also presented in Chapter 2. Signal detection in the presence of noise is generally formulated as a testing of hypothesis problem. Chapter 3 introduces principles of bootstrap hypothesis testing. The topics are introduced with interesting real life examples. Flow charts, typical in engineering literature, are used to aid explanations of the bootstrap hypothesis testing procedures. The bootstrap leads to second-order correction due to pivoting; this improvement in the results due to pivoting is also explained. In the second part of Chapter 3, signal processing is treated as a regression problem. The performance of the bootstrap for matched filters as well as constant false-alarm rate matched filters is also illustrated. Chapters 2 and 3 focus on estimation problems. Chapter 4 introduces bootstrap methods used in model selection. Due to the inherent structure of the subject matter, this chapter may be difficult for nonstatisticians to follow. Chapter 5 is the most impressive chapter in the book, especially from the standpoint of statisticians. It provides real data bootstrap applications to illustrate the theory covered in the earlier chapters. These include applications to optimal sensor placement for knock detection and land-mine detection. The authors also provide a MATLAB toolbox comprising frequently used routines. Overall, this is a very useful handbook for engineers, especially those working in signal processing.

Probability and Random Processes

Alternating direction method of multiplier (ADMM) is a widely used algorithm for solving constrained optimization problems in image restoration. Among many useful features, one critical feature of the ADMM algorithm is its modular structure, which allows one to plug in any off-the-shelf image denoising algorithm for a subproblem in the ADMM algorithm. Because of the plug-in nature, this type of ADMM algorithms is coined the name “Plug-and-Play ADMM.” Plug-and-Play ADMM has demonstrated promising empirical results in a number of recent papers. However, it is unclear under what conditions and by using what denoising algorithms would it guarantee convergence. Also, since Plug-and-Play ADMM uses a specific way to split the variables, it is unclear if fast implementation can be made for common Gaussian and Poissonian image restoration problems. In this paper, we propose a Plug-and-Play ADMM algorithm with provable fixed-point convergence. We show that for any denoising algorithm satisfying an asymptotic criteria, called bounded denoisers, Plug-and-Play ADMM converges to a fixed point under a continuation scheme. We also present fast implementations for two image restoration problems on superresolution and single-photon imaging. We compare Plug-and-Play ADMM with state-of-the-art algorithms in each problem type and demonstrate promising experimental results of the algorithm.

Plug-and-Play ADMM for Image Restoration: Fixed-Point Convergence and Applications

This paper presents a fast algorithm for restoring video sequences. The proposed algorithm, as opposed to existing methods, does not consider video restoration as a sequence of image restoration problems. Rather, it treats a video sequence as a space-time volume and poses a space-time total variation regularization to enhance the smoothness of the solution. The optimization problem is solved by transforming the original unconstrained minimization problem to an equivalent constrained minimization problem. An augmented Lagrangian method is used to handle the constraints, and an alternating direction method is used to iteratively find solutions to the subproblems. The proposed algorithm has a wide range of applications, including video deblurring and denoising, video disparity refinement, and hot-air turbulence effect reduction.

/pdf/an-augmented-lagrangian-method-for-total-variation-video-1d5wq82a9y.pdf

An Augmented Lagrangian Method for Total Variation Video Restoration

Alternating direction method of multiplier (ADMM) is a widely used algorithm for solving constrained optimization problems in image restoration. Among many useful features, one critical feature of the ADMM algorithm is its modular structure which allows one to plug in any off-the-shelf image denoising algorithm for a subproblem in the ADMM algorithm. Because of the plug-in nature, this type of ADMM algorithms is coined the name "Plug-and-Play ADMM". Plug-and-Play ADMM has demonstrated promising empirical results in a number of recent papers. However, it is unclear under what conditions and by using what denoising algorithms would it guarantee convergence. Also, since Plug-and-Play ADMM uses a specific way to split the variables, it is unclear if fast implementation can be made for common Gaussian and Poissonian image restoration problems. 
In this paper, we propose a Plug-and-Play ADMM algorithm with provable fixed point convergence. We show that for any denoising algorithm satisfying an asymptotic criteria, called bounded denoisers, Plug-and-Play ADMM converges to a fixed point under a continuation scheme. We also present fast implementations for two image restoration problems on super-resolution and single-photon imaging. We compare Plug-and-Play ADMM with state-of-the-art algorithms in each problem type, and demonstrate promising experimental results of the algorithm.

Plug-and-Play ADMM for Image Restoration: Fixed Point Convergence and Applications

Non-parametric approaches for analyzing network data based on exchangeable graph models (ExGM) have recently gained interest. The key object that defines an ExGM is often referred to as a graphon. This non-parametric perspective on network modeling poses challenging questions on how to make inference on the graphon underlying observed network data. In this paper, we propose a computationally efficient procedure to estimate a graphon from a set of observed networks generated from it. This procedure is based on a stochastic blockmodel approximation (SBA) of the graphon. We show that, by approximating the graphon with a stochastic block model, the graphon can be consistently estimated, that is, the estimation error vanishes as the size of the graph approaches infinity.

Stochastic blockmodel approximation of a graphon: Theory and consistent estimation

Magnetic resonance imaging (MRI) is a noninvasive diagnostic tool that provides excellent soft-tissue contrast without the use of ionizing radiation. Compared to other clinical imaging modalities (e.g., computed tomography or ultrasound), however, the data acquisition process for MRI is inherently slow, which motivates undersampling; thus, there is a need for accurate, efficient reconstruction methods from undersampled data sets. In this article, we describe the use of plug-and-play (PnP) algorithms for MRI image recovery. We first describe the linearly approximated inverse problem encountered in MRI. Then, we review several PnP methods for which the unifying commonality is to iteratively call a denoising subroutine as one step of a larger optimization-inspired algorithm. Next, we describe how the result of the PnP method can be interpreted as a solution to an equilibrium equation, allowing convergence analysis from this perspective. Finally, we present illustrative examples of PnP methods applied to MRI image recovery.

/pdf/plug-and-play-methods-for-magnetic-resonance-imaging-using-5btoa88zy5.pdf

Stanley H. Chan

Papers

Plug-and-Play ADMM for Image Restoration: Fixed-Point Convergence and Applications

An Augmented Lagrangian Method for Total Variation Video Restoration

Plug-and-Play ADMM for Image Restoration: Fixed Point Convergence and Applications

Stochastic blockmodel approximation of a graphon: Theory and consistent estimation

Plug-and-Play Methods for Magnetic Resonance Imaging: Using Denoisers for Image Recovery