S
Stanleyson V. Hato
Researcher at Radboud University Nijmegen
Publications - 31
Citations - 2621
Stanleyson V. Hato is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Cancer & T cell. The author has an hindex of 20, co-authored 31 publications receiving 2184 citations. Previous affiliations of Stanleyson V. Hato include Radboud University Nijmegen Medical Centre & University of Western Australia.
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Journal ArticleDOI
Molecular Pathways: The Immunogenic Effects of Platinum-Based Chemotherapeutics
TL;DR: The literature on the immunogenic effects of platinum is reviewed, the clinical advances using platinum as a cytotoxic compound with immune adjuvant properties are summarized, the limitations to these studies are discussed, and the gaps in the understanding of the immunologic effects of these drugs are discussed.
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Programmed Death Ligand 2 in Cancer-Induced Immune Suppression
TL;DR: The literature on the immunobiology of PD-L2 is reviewed, particularly on its possible roles in cancer-induced immune suppression and the results of recent studies targeting PD- L2 in cancer are discussed.
Journal ArticleDOI
Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis
Ellen H. van den Bogaard,Judith G.M. Bergboer,Mieke Vonk-Bergers,Ivonne M.J.J. van Vlijmen-Willems,Stanleyson V. Hato,Pieter G. M. Van Der Valk,Jens Michael Schröder,Irma Joosten,Patrick L.J.M. Zeeuwen,Joost Schalkwijk +9 more
TL;DR: The therapeutic effect of AHR activation herein described opens a new avenue to reconsider AHR as a pharmacological target and could lead to the development of mechanism-based drugs for AD.
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Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice
W. Joost Lesterhuis,Cornelis J. A. Punt,Stanleyson V. Hato,Dagmar Eleveld-Trancikova,Bastiaan J.H. Jansen,Stefan Nierkens,Gerty Schreibelt,Annemiek J. de Boer,Carla M.L. van Herpen,Johannes H.A.M. Kaanders,Johan H. J. M. van Krieken,Gosse J. Adema,Carl G. Figdor,I. Jolanda M. de Vries +13 more
TL;DR: It is concluded that platinum-based anticancer drugs can enhance the immunostimulatory potential of DCs and decrease the immunosuppressive capability of tumor cells.
Journal ArticleDOI
Dendritic Cell Interaction with Candida albicans Critically Depends on N-Linked Mannan
Alessandra Cambi,Mihai G. Netea,Héctor M. Mora-Montes,Neil A. R. Gow,Stanleyson V. Hato,Douglas W. Lowman,Douglas W. Lowman,Bart Jan Kullberg,Ruurd Torensma,David L. Williams,Carl G. Figdor +10 more
TL;DR: It is determined that N-linked mannan but not O-linked or phosphomannan is the fungal carbohydrate structure specifically recognized by both C-type lectins on human DCs and directly influences the production of the proinflammatory cytokine IL-6.