Stefan Recknagel

TL;DR: Evidence suggests that insufficient biomechanical conditions within the fracture zone can influence early local inflammation and impair bone healing, with particular emphasis on the role of inflammation.

TL;DR: Investigation of the presence and function of complement in bone cells including osteoblasts, mesenchymal stem cells (MSC), and osteoclasts found that complement may modulate the inflammatory response of osteoblastic cells in a pro‐inflammatory environment as well as osteoblast–osteoclast interaction.

TL;DR: A review of the advantages and pitfalls of different fixation techniques in rats and mice can be found in this article, with a focus on the elucidation of molecular mechanisms of fracture healing using the largely available spectrum of antibodies and gene-targeted animals.

TL;DR: It is suggested that C5aR might play a regulatory role in fracture healing in intramembranous and in enchondral ossification, one possible function being the regulation of cell recruitment.

TL;DR: It is reported for the first time that a blunt chest trauma considerably impaired bone healing, possibly via the interaction of the induced systemic inflammation with local inflammatory processes.