S
Stefano F. Liparoto
Researcher at Biogen Idec
Publications - 1
Citations - 179
Stefano F. Liparoto is an academic researcher from Biogen Idec. The author has contributed to research in topics: Protein–protein interaction & Affinity maturation. The author has an hindex of 1, co-authored 1 publications receiving 167 citations.
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Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design
Louis A. Clark,P. Ann Boriack-Sjodin,John Eldredge,Christopher Fitch,Bethany Friedman,Karl J. M. Hanf,Matthew Jarpe,Stefano F. Liparoto,You Li,Alexey Lugovskoy,Miller Stephan S,Mia Rushe,Woody Sherman,Kenneth Simon,Herman W. T. van Vlijmen +14 more
TL;DR: The results indicate that structure‐based computational design can be successfully applied to further improve the binding of high‐affinity antibodies and improve the single‐mutant success rate.