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Steffen Klamt
Researcher at Max Planck Society
Publications - 122
Citations - 9623
Steffen Klamt is an academic researcher from Max Planck Society. The author has contributed to research in topics: Metabolic network & Flux (metabolism). The author has an hindex of 46, co-authored 112 publications receiving 8608 citations.
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Metabolic network structure determines key aspects of functionality and regulation
TL;DR: A theoretical method for simultaneously predicting key aspects of network functionality, robustness and gene regulation from network structure alone is devised by determining and analysing the non-decomposable pathways able to operate coherently at steady state (elementary flux modes).
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Structural and functional analysis of cellular networks with CellNetAnalyzer
TL;DR: CellNetAnalyzer is introduced, a toolbox for MATLAB facilitating, in an interactive and visual manner, a comprehensive structural analysis of metabolic, signalling and regulatory networks and provides a large toolbox with various, partially unique, functions and algorithms for functional network analysis.
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Hypergraphs and cellular networks.
TL;DR: This paper presents a meta-analyses of the dynamic response of the immune system to infectious disease and shows clear trends in immune-inflammatory bowel disease and central nervous system disorders.
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A methodology for the structural and functional analysis of signaling and regulatory networks
TL;DR: This work proposes formalisms and methods, relying on adapted and partially newly introduced approaches, which facilitate a structural analysis of signaling and regulatory networks with focus on functional aspects, and proposes a formalism based on logical interaction hypergraphs, which facilitates a logical steady state analysis (LSSA).
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Comparison of network-based pathway analysis methods
Jason A. Papin,Joerg Stelling,Nathan D. Price,Steffen Klamt,Stefan Schuster,Bernhard O. Palsson +5 more
TL;DR: The relationship between elementary modes and extreme pathways of previously published metabolic reconstructions of the human red blood cell and the human pathogen Helicobacter pylori are compared and contrasted.