S
Stella Cascioferro
Researcher at University of Palermo
Publications - 96
Citations - 2501
Stella Cascioferro is an academic researcher from University of Palermo. The author has contributed to research in topics: Biofilm & Medicine. The author has an hindex of 22, co-authored 88 publications receiving 1718 citations.
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Sortase A: An ideal target for anti-virulence drug development
TL;DR: This review is focused on the most promising sortase A inhibitor compounds that are currently in development as leads towards a new class of anti-infective drugs that are urgently needed to help combat the alarming increase in antimicrobial resistance.
Sortase A : an ideal target for anti-virulence drug development
TL;DR: The most promising sortase A inhibitor compounds that are currently in development as leads towards a new class of anti-infective drugs that are urgently needed to help combat the alarming increase in antimicrobial resistance are presented in this paper.
Journal ArticleDOI
Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms
Domenico Schillaci,Virginia Spanò,Barbara Parrino,Anna Carbone,Alessandra Montalbano,Paola Barraja,Patrizia Diana,Girolamo Cirrincione,Stella Cascioferro +8 more
TL;DR: This Perspective is on chemical agents that target the most common mechanisms of antibiotic resistance such as enzymatic inactivation of antibiotics, changes in cell permeability, and induction/activation of efflux pumps.
Journal ArticleDOI
Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance.
Barbara Parrino,Domenico Schillaci,Ilaria Carnevale,Elisa Giovannetti,Elisa Giovannetti,Patrizia Diana,Girolamo Cirrincione,Stella Cascioferro +7 more
TL;DR: The most relevant literature of the last decade is selected, focusing on the development of synthetic small molecules able to prevent bacterial biofilm formation or to eradicate pre-existing biofilms of clinically relevant Gram-positive and Gram-negative pathogens.
Journal ArticleDOI
Sortase A Inhibitors: Recent Advances and Future Perspectives.
Stella Cascioferro,Demetrio Raffa,Benedetta Maggio,Maria Valeria Raimondi,Domenico Schillaci,Giuseppe Daidone +5 more
TL;DR: The most promising small synthetic organic compounds that act as potent Sortase A inhibitors and cater the potential to be developed as antivirulence drugs are described.