Stéphanie Trumtel

TL;DR: It is proposed that the dynamic interaction of Noc proteins is crucial for intranuclear movement of ribosomal precursor particles, and, thereby represent a prerequisite for proper maturation.

TL;DR: By combining cryofixation and cryosubstitution in a structural and functional analysis of the nucleus of Saccharomyces cerevisiae, morphological subcompartments in the nucleolus are identified and it is suggested that ribosomal transcripts are distributed along a nucleolar network that might include both DFC and GC.

TL;DR: It is shown that changing parameters as critical as the tandem organization of the ribosomal genes and the polymerase transcribing rDNA, although profoundly modifying the position and the shape of the nucleolus, only partially alter its functional subcompartmentation.