S
Stephen Brown
Researcher at University of Sheffield
Publications - 63
Citations - 3865
Stephen Brown is an academic researcher from University of Sheffield. The author has contributed to research in topics: JAK-STAT signaling pathway & Cancer. The author has an hindex of 27, co-authored 58 publications receiving 3595 citations. Previous affiliations of Stephen Brown include University of Manchester & University of Nottingham.
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The genome of the model beetle and pest Tribolium castaneum
Stephen Richards,R. A. Gibbs,George M. Weinstock,Susan J. Brown,R. E. Denell,Richard W. Beeman,Richard A. Gibbs,Gregor Bucher,Markus Friedrich,Cornelis J. P. Grimmelikhuijzen,Martin Klingler,Marcé D. Lorenzen,Siegfried Roth,Reinhard Schröder,Diethard Tautz,Evgeny M. Zdobnov,Donna M. Muzny,Tony Attaway,Stephanie Bell,Christian J. Buhay,Mimi N. Chandrabose,Dean Chavez,KP Clerk-Blankenburg,Andy Cree,Marvin Diep Dao,Clay Davis,Joseph Chacko,Huyen Dinh,Shannon Dugan-Rocha,Gerald R. Fowler,Toni T. Garner,Jeffrey Garnes,Andreas Gnirke,Alicia Hawes,Judith Hernandez,Sandra Hines,M. Holder,Jennifer Hume,Shalini N. Jhangiani,Joshi,Ziad Khan,LaRonda Jackson,Christie Kovar,A Kowis,Sandra L. Lee,Lora Lewis,Jonathan Margolis,Michael J. Morgan,Lynne V. Nazareth,Ngoc Nguyen,Geoffrey Okwuonu,David Parker,San Juana Ruiz,Jireh Santibanez,Joël Savard,Steve Scherer,Brian W. Schneider,Erica Sodergren,S Vattahil,Donna Villasana,Courtney Sherell White,Rita A. Wright,Yoonseong Park,Joanne Lord,Brenda Oppert,Stephen Brown,Liangjiang Wang,G Weinstock,Yue Liu,Kim C. Worley,Christine G. Elsik,Justin T. Reese,Eran Elhaik,Giddy Landan,Dan Graur,Peter Arensburger,Peter W. Atkinson,J Beidler,Jeffery P. Demuth,Douglas W. Drury,YZ Du,Haruhiko Fujiwara,Maselli,Mizuko Osanai,Hugh M. Robertson,Zhijian Tu,Jianjun Wang,Suzhi Wang,Henry Song,Lan Zhang,Doreen Werner,Mario Stanke,Burkhard Morgenstern,Solovyev,Peter Kosarev,Garth Brown,Hsiu Chuan Chen,Olga Ermolaeva,Wratko Hlavina,Yuri Kapustin +99 more
TL;DR: Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products as discussed by the authors.
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Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless
TL;DR: It is shown that domeless (dome) codes for a transmembrane protein required for all JAK/STAT functions in the Drosophila embryo, which suggests that the vertebrate families evolved from a single ancestral receptor that also gave rise to dome.
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The red flour beetle's large nose: An expanded odorant receptor gene family in Tribolium castaneum
Patamarerk Engsontia,Alan P. Sanderson,Matthew Cobb,Kimberly K. O. Walden,Hugh M. Robertson,Stephen Brown +5 more
TL;DR: Beetle pupae were injected with TcOr1 dsRNA; unlike sham-injected and control beetles, these knock-down beetles showed no significant response to the Tribolium aggregation pheromone, supporting the hypothesis that T cOr1 plays a similar decisive role in olfaction to DmOr83b.
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Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand.
TL;DR: The analysis of the only invertebrate JAK/STAT pathway ligands identified to date, the Drosophila unpaired-like family is described, showing that upd2 is expressed in a pattern essentially identical to that of upd and it is demonstrated that the proteins encoded by this region activate JAK-STAT pathway signalling.
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The fertile field of Drosophila Jak/STAT signalling.
TL;DR: Current knowledge of the JAK/STAT pathway is described and genome data is used to discuss what elements are present in Drosophila, providing the first molecular characterisation of a stem cell niche.