S
Stephen D. Bell
Researcher at Indiana University
Publications - 121
Citations - 8315
Stephen D. Bell is an academic researcher from Indiana University. The author has contributed to research in topics: DNA replication & Origin recognition complex. The author has an hindex of 54, co-authored 117 publications receiving 7874 citations. Previous affiliations of Stephen D. Bell include University of Oxford & Anderson University (Indiana).
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Journal ArticleDOI
A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters.
Alexandra Kessler,Alexandra Kessler,Guennadi Sezonov,J. Iñaki Guijarro,Nicole Desnoues,Thierry Rose,Muriel Delepierre,Stephen D. Bell,David Prangishvili +8 more
TL;DR: This strategy of the archaeal virus to co-opt a host cell regulator to promote transcription of its genes resembles eukaryal virus–host relationships.
Journal ArticleDOI
Molecular machines in archaeal DNA replication
TL;DR: Recent advances in understanding the properties of the replicative helicase, the MCM complex, and the role of the sliding clamp, PCNA, in mediating a range of protein-DNA transactions are described.
Journal ArticleDOI
Extra-chromosomal elements and the evolution of cellular DNA replication machineries
Adam T. McGeoch,Stephen D. Bell +1 more
TL;DR: The role that lateral gene transfer by extra-chromosomal elements might have had in shaping the replication machinery and even modulating the manner in which host cellular genomes are replicated is discussed.
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A Complex Endomembrane System in the Archaeon Ignicoccus hospitalis Tapped by Nanoarchaeum equitans.
Thomas Heimerl,Jennifer Flechsler,Carolin Pickl,Veronika Heinz,Benjamin Salecker,Josef Zweck,Gerhard Wanner,Stefan Geimer,Rachel Y. Samson,Stephen D. Bell,Harald Huber,Reinhard Wirth,Louie L. Wurch,Louie L. Wurch,Mircea Podar,Mircea Podar,Reinhard Rachel +16 more
TL;DR: Overall, this unusual cellular compartmentalization, ultrastructure and dynamics in an archaeon that belongs to the recently proposed TACK superphylum prompts speculation that the eukaryotic endomembrane system might originate from Archaea.
Journal ArticleDOI
Identification of a Conserved Archaeal RNA Polymerase Subunit Contacted by the Basal Transcription Factor TFB
TL;DR: Using systematic yeast two-hybrid and biochemical analyses, an interaction between the N-terminal domain of TFB and an evolutionarily conserved subunit of the RNA polymerase, RpoK is identified.