Stephen G. Rostand

TL;DR: Overall analyses, intensive blood-pressure control had no effect on kidney disease progression, however, there may be differential effects of intensiveBlood pressure control in patients with and those without baseline proteinuria, as well as according to the baseline level of proteinuria.

TL;DR: The hyperparathyroid state and altered vitamin D status found in Uremia contribute to the cardiovascular pathology seen clinically in uremia and also to the excess mortality from cardiovascular causes found in this patient group.

TL;DR: Reduced epidermal vitamin D3 photosynthesis associated with high skin melanin content and/or decreased UV light intensity at distances from the equator, alone or when coupled with decreased dietary calcium and vitamin D, may be associated with reduced vitamin D stores and increased parathyroid hormone secretion.

TL;DR: The number of patients undergoing treatment for end-stage renal disease (ESRD) has increased dramatically since 1973, when Medicare began funding its treatment and is now much greater than the number in the most economically and technologically advanced countries of Europe.

TL;DR: Baseline proteinuria and GFR predicted the rgate of GFR decline and initial change in proteinuria from baseline to 6 months predicted subsequent progression, with this relationship extending to participants with baseline urinary protein levels less than 300 mg/d.