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Stuart R. Weiss

Researcher at Merck & Co.

Publications -  34
Citations -  7299

Stuart R. Weiss is an academic researcher from Merck & Co.. The author has contributed to research in topics: Simvastatin & Bone mineral. The author has an hindex of 27, co-authored 34 publications receiving 7165 citations.

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Effect of Oral Alendronate on Bone Mineral Density and the Incidence of Fractures in Postmenopausal Osteoporosis

TL;DR: Daily treatment with alendronate progressively increases the bone mass in the spine, hip, and total body and reduces the incidence of vertebral fractures, the progression of vertebra deformities, and height loss in postmenopausal women with osteoporosis.
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Efficacy and safety of ezetimibe added to ongoing statin therapy for treatment of patients with primary hypercholesterolemia.

TL;DR: Adding ezetimibe to ongoing statin therapy led to substantial additional reduction in LDL cholesterol levels, facilitating attainment of NCEP goals and offers a new therapeutic option for patients receiving statins who require further reduction in cholesterol levels.
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Reduction of LDL Cholesterol by 25% to 60% in Patients With Primary Hypercholesterolemia by Atorvastatin, a New HMG-CoA Reductase Inhibitor

TL;DR: Atorvastatin was well tolerated by hyperlipidemic patients, had an acceptable safety profile, and provided greater reduction in cholesterol than other previously reported HMG-CoA reductase inhibitors.
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Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia.

TL;DR: Total serum triglyceride levels decreased in a dose-dependent manner, reductions in the 20-mg and 80-mg groups were statistically significant and atorvastatin did not cause a redistribution of triglycerides but consistently lowered triglycerides in all lipoprotein fractions.