S
Sueva Cantalupo
Researcher at University of Naples Federico II
Publications - 23
Citations - 241
Sueva Cantalupo is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 6, co-authored 12 publications receiving 74 citations.
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Journal ArticleDOI
HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia
Flora Cimmino,Marianna Avitabile,Vito Alessandro Lasorsa,Annalaura Montella,Lucia Pezone,Sueva Cantalupo,Feliciano Visconte,Maria Valeria Corrias,Achille Iolascon,Mario Capasso +9 more
TL;DR: A combined analysis of RNA expression and DNA methylation of neuroblastoma cells silenced or unsilenced for HIF1A expression may help to understand the molecular mechanisms by which low oxygen levels reshape gene signatures and provide new direction for hypoxia targeting in solid tumor.
Journal ArticleDOI
Common variants at 21q22.3 locus influence MX1 and TMPRSS2 gene expression and susceptibility to severe COVID-19.
Immacolata Andolfo,Roberta Russo,Vito Alessandro Lasorsa,Sueva Cantalupo,Barbara Eleni Rosato,Ferdinando Bonfiglio,Giulia Frisso,Pasquale Abete,Gian Marco Cassese,Giuseppe Servillo,Gabriella Esposito,Ivan Gentile,Carmelo Piscopo,Romolo Villani,Giuseppe Fiorentino,Pellegrino Cerino,Carlo Buonerba,Biancamaria Pierri,Massimo Zollo,Achille Iolascon,Mario Capasso +20 more
TL;DR: In this article, the authors performed an in-depth genetic analysis of chromosome 21 exploiting the genome-wide association study data, including 6,406 individuals hospitalized for COVID-19 and 902,088 controls with European genetic ancestry from the COVID19 Host Genetics Initiative.
Journal ArticleDOI
Genetic Predisposition to Solid Pediatric Cancers.
Mario Capasso,Annalaura Montella,Matilde Tirelli,Teresa Maiorino,Sueva Cantalupo,Achille Iolascon +5 more
TL;DR: An overview of genetic variations predisposing to solid pediatric tumors is provided and the emerging view that interactions between germline and somatic alterations are a key determinant of cancer development is emphasized.
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Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene
Marianna Avitabile,Mariangela Succoio,Alessandro Testori,Antonella Cardinale,Zalman Vaksman,Zalman Vaksman,Vito Alessandro Lasorsa,Sueva Cantalupo,Matteo Esposito,Flora Cimmino,Annalaura Montella,Daniela Formicola,Jan Koster,Virginia Andreotti,Paola Ghiorzo,Maria Fiammetta Romano,Stefania Staibano,Massimiliano Scalvenzi,Fabrizio Ayala,Hakon Hakonarson,Hakon Hakonarson,Maria Valeria Corrias,Marcella Devoto,Marcella Devoto,Marcella Devoto,Matthew Law,Mark M. Iles,Kevin M. Brown,Sharon J. Diskin,Sharon J. Diskin,Nicola Zambrano,Achille Iolascon,Mario Capasso +32 more
TL;DR: It is demonstrated that combining genome-wide association studies results across cancers with same origins can identify new loci common to neuroblastoma and melanoma arising from tissues which originate from neural crest cells.
Journal ArticleDOI
Transcription Factors Involved in Tumorigenesis Are Over-Represented in Mutated Active DNA-Binding Sites in Neuroblastoma.
Mario Capasso,Vito Alessandro Lasorsa,Flora Cimmino,Marianna Avitabile,Sueva Cantalupo,Annalaura Montella,Biagio De Angelis,Martina Morini,Carmen de Torres,Aurora Castellano,Franco Locatelli,Achille Iolascon +11 more
TL;DR: A novel approach is proposed to study the involvement of regulatory variants in NB that could be extended to other cancers and provide further evidence that alterations of gene expression may have relevant effects in NB development.