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Sumiko Inoue
Researcher at Kyoto University
Publications - 51
Citations - 3884
Sumiko Inoue is an academic researcher from Kyoto University. The author has contributed to research in topics: DNA damage & Guanine. The author has an hindex of 34, co-authored 50 publications receiving 3587 citations. Previous affiliations of Sumiko Inoue include Mie University.
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Journal ArticleDOI
Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
Sumiko Inoue,Shosuke Kawanishi +1 more
TL;DR: The results suggest that NO reacts with O2 − to form peroxynitrite and the peroxlynitrite induces oxidative DNA damage through an active intermediate of which reactivity is similar to •OH.
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Mechanism of DNA cleavage induced by sodium chromate(VI) in the presence of hydrogen peroxide.
TL;DR: Results indicate that sodium chromate(VI) reacts with hydrogen peroxide to form tetraperoxochromate(V), leading to the production of the hydroxyl radical, which causes every base alteration and deoxyribose-phosphate backbone breakage.
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8-Hydroxydeoxyguanosine formation at the 5' site of 5'-GG-3' sequences in double-stranded DNA by UV radiation with riboflavin.
TL;DR: The estimated ratio of 8-OH-dG yield to total guanine loss indicates that the photoexcited riboflavin induces 8- OH- dG formation specifically at the guanin residue located 5' to guanines through electron transfer.
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Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder.
Robert Kleta,Elisa Romeo,Zorica Ristic,Toshihiro Ohura,C Stuart,Mauricio Arcos-Burgos,Mital H. Dave,Carsten A. Wagner,Simone R M Camargo,Sumiko Inoue,Norio Matsuura,Amanda Helip-Wooley,Detlef Bockenhauer,Richard Warth,Isa Bernardini,Gepke Visser,Thomas Eggermann,Philip Lee,Arthit Chairoungdua,Promsuk Jutabha,Ellappan Babu,Sirinun Nilwarangkoon,Naohiko Anzai,Yoshikatsu Kanai,François Verrey,William A. Gahl,Akio Koizumi +26 more
TL;DR: The protein product of SLC6A19, the Hartnup transporter, is expressed primarily in intestine and renal proximal tubule and functions as a neutral amino acid transporter.
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Genetic epidemiology of hereditary hemorrhagic telangiectasia in a local community in the northern part of Japan.
Miwako Dakeishi,Takanobu Shioya,Yasuhiko Wada,T. Shindo,Kousei Otaka,Motomu Manabe,Jun-ichi Nozaki,Jun-ichi Nozaki,Sumiko Inoue,Akio Koizumi,Akio Koizumi +10 more
TL;DR: It is recommended that families with HHT be screened for gene mutations in order that high‐risk individuals receive early diagnosis and treatment initiation that will substantially alter their clinical course and prognosis.