Surface plasmons (SPs) are coherent oscillations of conduction electrons on a metal surface excited by electromagnetic radiation at a metal -dielectric interface. The growing field of research on such light -metal interactions is known as ‘plasmonics’. 1-3 This branch of research has attracted much attention due to its potential applications in miniaturized optical devices, sensors, and photonic circuits as well as in medical diagnostics and therapeutics. 4-8

Nanostructured plasmonic sensors.

Heavy metal removal from water/wastewater by nanosized metal oxides: a review.

In this article, several applications of nanomaterials in food packaging and food safety are reviewed, including: polymer/clay nanocomposites as high barrier packaging materials, silver nanoparticles as potent antimicrobial agents, and nanosensors and nanomaterial-based assays for the detection of food-relevant analytes (gasses, small organic molecules and food-borne pathogens). In addition to covering the technical aspects of these topics, the current commercial status and understanding of health implications of these technologies are also discussed. These applications were chosen because they do not involve direct addition of nanoparticles to consumed foods, and thus are more likely to be marketed to the public in the short term.

Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors

Recent Trends in Macro-, Micro-, and Nanomaterial-Based Tools and Strategies for Heavy-Metal Detection Gemma Aragay, Josefina Pons, and Arben Merkoc-i* Nanobioelectronics & Biosensors Group, Institut Catal a de Nanotecnologia (CIN2, ICN-CSIC), 08193, Bellaterra, Barcelona, Spain Departament of Chemistry, Universitat Aut onoma de Barcelona, 08193, Bellaterra, Barcelona, Spain ICREA, Barcelona, Spain

Recent trends in macro-, micro-, and nanomaterial-based tools and strategies for heavy-metal detection.

Towards integrated and sensitive surface plasmon resonance biosensors: a review of recent progress.

The detection and characterization of protein aggregates are critical in terms of advanced diagnostic applications and investigations of protein stability A variety of analytical methods (eg, circular dichroism, size exclusion chromatography, and fluorescence microscopy) have been used in this regard, but they are limited in the trace detection of the structural evolution of protein aggregation Here we report the gold nanoparticle (AuNP)-based highly sensitive and colorimetric detection of the temporal evolution of superoxide dismutase (SOD1) aggregates implicated in the pathology of amyotrophic lateral sclerosis (ALS) For the temporal discrimination of SOD1 aggregation, AuNPs were conjugated with SOD1 monomers (SOD1-AuNPs) Upon exposure of the probes (SOD1-AuNPs) with SOD1 aggregates, significant changes in both surface plasmon resonance spectra and concomitant colors were observed which are attributed to the formation of probe aggregates of variable sizes onto the SOD1 aggregates

Sensitive and colorimetric detection of the structural evolution of superoxide dismutase with gold nanoparticles.

Preparation of novel ceramic membranes modified by mesoporous silica with 3-aminopropyltriethoxysilane (APTES) and its application to Cu2+ separation in the aqueous phase

Surface plasmon resonance analysis of aqueous copper ions with amino-terminated self-assembled monolayers

A new class of surface-immobilized protein nanomachines can be reversibly actuated by cycling the solution pH between 2.5 and 12.3, which induces a conformational change, thereby modulating the thickness of superoxide dismutase (SOD1) tethered to the Au thin film. By placing Au nanoparticles (AuNP) atop the immobilized SOD1 by means of a gold-thiol assembly, the nanoscale motion of SOD1 at the interface produces mechanical work to lift and then lower the AuNP from the Au substrate by a distance of ca. 3 nm and transduces this motion into an easily measurable reflectivity change in the surface plasmon resonance (SPR) spectrum. As-made supported conjugate consisting of SOD1 and AuNP is quite robust and stable, and its operation in response to pH variations, which mirrors the conformational changes of responsive SOD1 at the interface, is found to be highly reversible and reproducible. This is the first demonstration of the development of novel solid-state sensors and/or switching devices based on substrate-bound protein conformational changes and AuNP enhanced SPR spectroscopy.

Surin Hong

Papers

Sensitive and colorimetric detection of the structural evolution of superoxide dismutase with gold nanoparticles.

Preparation of novel ceramic membranes modified by mesoporous silica with 3-aminopropyltriethoxysilane (APTES) and its application to Cu2+ separation in the aqueous phase

Surface plasmon resonance analysis of aqueous copper ions with amino-terminated self-assembled monolayers

Reversible pH-driven conformational switching of tethered superoxide dismutase with gold nanoparticle enhanced surface plasmon resonance spectroscopy.

Total synthesis of pamamycin-607.