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Susan J Dutton
Researcher at University of Oxford
Publications - 153
Citations - 5994
Susan J Dutton is an academic researcher from University of Oxford. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 29, co-authored 123 publications receiving 4549 citations. Previous affiliations of Susan J Dutton include St George's, University of London & National Council of Resistance of Iran.
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Journal ArticleDOI
A randomized trial of normothermic preservation in liver transplantation
D Nasralla,Constantin C. Coussios,Hynek Mergental,M. Zeeshan Akhtar,Andrew J. Butler,Carlo D L Ceresa,Virginia Chiocchia,Susan J Dutton,Juan Carlos García-Valdecasas,Nigel Heaton,Charles Imber,Wayel Jassem,Ina Jochmans,John Karani,Simon R. Knight,Simon R. Knight,Peri Kocabayoglu,Massimo Malagó,Darius F. Mirza,Peter J. Morris,Peter J. Morris,Arvind Pallan,Andreas Paul,Mihai Pavel,M. Thamara P. R. Perera,Jacques Pirenne,R. Ravikumar,Leslie James Russell,Sara Upponi,Christopher J.E. Watson,Annemarie Weissenbacher,Rutger J. Ploeg,Peter J. Friend +32 more
TL;DR: Normothermic machine perfusion of the liver improved early graft function, demonstrated by reduced peak serum aspartate transaminase levels and early allograft dysfunction rates, and improved organ utilization and preservation times, although no differences were seen in graft or patient survival.
Journal ArticleDOI
Reporting and interpretation of randomized controlled trials with statistically nonsignificant results for primary outcomes.
TL;DR: The reporting and interpretation of findings was frequently inconsistent with the results and the nature and frequency of distorted presentation or "spin" was identified in published reports of randomized controlled trials with statistically nonsignificant results for primary outcomes.
Journal ArticleDOI
External validation of multivariable prediction models: a systematic review of methodological conduct and reporting.
Gary S. Collins,Joris A. H. de Groot,Susan J Dutton,Omar Omar,Milensu Shanyinde,Abdelouahid Tajar,Merryn Voysey,R Wharton,Ly-Mee Yu,Karel G.M. Moons,Douglas G. Altman +10 more
TL;DR: The vast majority of studies describing some form of external validation of a multivariable prediction model were poorly reported with key details frequently not presented and calibration often omitted from the publication.
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The quality of reports of randomised trials in 2000 and 2006: comparative study of articles indexed in PubMed
TL;DR: Reporting of several important aspects of trial methods improved between 2000 and 2006; however, the quality of reporting remains well below an acceptable level.
Journal ArticleDOI
Gefitinib for oesophageal cancer progressing after chemotherapy (COG): a phase 3, multicentre, double-blind, placebo-controlled randomised trial
Susan J Dutton,D. R. Ferry,Jane M Blazeby,Jane M Blazeby,Haider Abbas,Asa Dahle-Smith,Wasat Mansoor,Joyce Thompson,Mark Harrison,Anirban Chatterjee,Stephen Falk,Angel Garcia-Alonso,D. Fyfe,Richard A Hubner,Tina Gamble,Lynnda Peachey,Mina Davoudianfar,Sarah Pearson,Patrick Julier,Janusz Jankowski,Rachel Kerr,Russell D. Petty +21 more
TL;DR: The use of gefitinib as a second-line treatment in oesophageal cancer in unselected patients does not improve overall survival, but has palliative benefits in a subgroup of patients with short life expectancy.