S
Susan M. Lantz-McPeak
Researcher at National Center for Toxicological Research
Publications - 3
Citations - 170
Susan M. Lantz-McPeak is an academic researcher from National Center for Toxicological Research. The author has contributed to research in topics: Dopaminergic & High-content screening. The author has an hindex of 3, co-authored 3 publications receiving 132 citations.
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Journal ArticleDOI
Developmental toxicity assay using high content screening of zebrafish embryos
Susan M. Lantz-McPeak,Xiaoqing Guo,Elvis Cuevas,Melanie Dumas,Glenn D. Newport,Syed F. Ali,Merle G. Paule,Jyotshna Kanungo +7 more
TL;DR: An automated image‐based high content screening (HCS) assay to identify the teratogenic/embryotoxic potential of compounds in zebrafish embryos in vivo and can significantly expedite the screening of potential teratogens and developmental toxicants in a high throughput manner.
Journal ArticleDOI
Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage
Syed Z. Imam,Susan M. Lantz-McPeak,Elvis Cuevas,Hector Rosas-Hernandez,Serguei Liachenko,Yongbin Zhang,Sumit Sarkar,Jaivijay Ramu,Bonnie L. Robinson,Yvonne Jones,Bobby Gough,Merle G. Paule,Syed F. Ali,Zbigniew Binienda +13 more
TL;DR: The data demonstrate a neurotoxic potential of very small size iron nanoparticles and suggest that use of these ferric oxide nanoparticles may result in neurotoxicity, thereby limiting their clinical application.
Journal ArticleDOI
Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles.
William J. Trickler,Susan M. Lantz-McPeak,Bonnie L. Robinson,Merle G. Paule,William Slikker,Alexandru S. Biris,John J. Schlager,Saber M. Hussain,Jyotshna Kanungo,Carmen G. Gonzalez,Syed F. Ali +10 more
TL;DR: The composition and size of NPs can cause significant pro-inflammatory response that can influence the integrity of the blood–brain barrier (BBB) in vitro.