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Susanna Mlynarczyk-Evans
Researcher at Stanford University
Publications - 11
Citations - 2012
Susanna Mlynarczyk-Evans is an academic researcher from Stanford University. The author has contributed to research in topics: Homologous chromosome & Synapsis. The author has an hindex of 10, co-authored 11 publications receiving 1893 citations. Previous affiliations of Susanna Mlynarczyk-Evans include University of California, San Francisco.
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Journal ArticleDOI
Role of histone H3 lysine 27 methylation in X inactivation.
Kathrin Plath,Jia Fang,Susanna Mlynarczyk-Evans,Ru Cao,Kathleen A. Worringer,Hengbin Wang,Cecile C. de la Cruz,Arie P. Otte,Barbara Panning,Yi Zhang +9 more
TL;DR: It is demonstrated that transient recruitment of the Eed-Ezh2 complex to the inactive X chromosome (Xi) occurs during initiation of X inactivation in both extraembryonic and embryonic cells and is accompanied by H3-K27 methylation.
Journal ArticleDOI
Xist RNA and the Mechanism of X Chromosome Inactivation
TL;DR: The authors are on the threshold of discovering the factors that regulate and interact with Xist to control X-inactivation, and closer to an understanding of the molecular mechanisms that underlie this complex process.
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The Synaptonemal Complex Shapes the Crossover Landscape Through Cooperative Assembly, Crossover Promotion and Crossover Inhibition During Caenorhabditis elegans Meiosis
TL;DR: The data suggest that the CO landscape is shaped by a combination of three attributes of the SC central region: a CO-promoting activity that functions locally at CO sites, a cooperative assembly process that enables CO formation in regions distant from prominent sites of synapsis initiation, and CO-inhibitory role(s) that limit CO number.
Journal ArticleDOI
X chromosomes alternate between two states prior to random X-inactivation
Susanna Mlynarczyk-Evans,Morgan Royce-Tolland,Mary Kate Alexander,Angela A Andersen,Sundeep Kalantry,Joost Gribnau,Barbara Panning +6 more
TL;DR: This work proposes a model in which the concerted switching of homologous X chromosomes between mutually exclusive future active and future inactive states provides the basis for the apparently random silencing of one X chromosome in female cells.
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Chromosome Painting Reveals Asynaptic Full Alignment of Homologs and HIM-8–Dependent Remodeling of X Chromosome Territories during Caenorhabditis elegans Meiosis
TL;DR: In this article, the authors investigate global features of chromosome organization during early meiotic prophase, using a chromosome painting method in whole-mount Caenorhabditis elegans gonads that enables visualization of whole chromosomes along their entire lengths in the context of preserved 3D nuclear architecture.