D
Dmitri A. Nusinow
Researcher at Donald Danforth Plant Science Center
Publications - 59
Citations - 4981
Dmitri A. Nusinow is an academic researcher from Donald Danforth Plant Science Center. The author has contributed to research in topics: Circadian clock & Arabidopsis. The author has an hindex of 25, co-authored 53 publications receiving 4068 citations. Previous affiliations of Dmitri A. Nusinow include University of California, San Diego & Washington University in St. Louis.
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Journal ArticleDOI
FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis.
TL;DR: The FKF1-GI complex forms on the CO promoter in late afternoon to regulate CO expression, providing a mechanistic view of how the coincidence of light with circadian timing regulates photoperiodic flowering.
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The ELF4–ELF3–LUX complex links the circadian clock to diurnal control of hypocotyl growth
Dmitri A. Nusinow,Anne Helfer,Elizabeth E. Hamilton,Jasmine J. King,Takato Imaizumi,Takato Imaizumi,Thomas F. Schultz,Thomas F. Schultz,Eva M. Farré,Eva M. Farré,Steve A. Kay +10 more
TL;DR: The evening complex underlies the molecular basis for circadian gating of hypocotyl growth in the early evening, and mutations in PIF4 and/or PIF5 are epistatic to the loss of the ELF4–ELF3–LUX complex, suggesting that regulation of Pif4 and PIF 5 is a crucial function of the complex.
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Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis
Eric E. Zhang,Yi Liu,Yi Liu,Renaud Dentin,Pagkapol Y. Pongsawakul,Andrew C. Liu,Andrew C. Liu,Andrew C. Liu,Tsuyoshi Hirota,Tsuyoshi Hirota,Dmitri A. Nusinow,Xiujie Sun,Severine Landais,Yuzo Kodama,David A. Brenner,Marc Montminy,Steve A. Kay +16 more
TL;DR: It is shown that Creb activity during fasting is modulated by Cry1 and Cry2, which are rhythmically expressed in the liver, which suggest that compounds that enhance cryptochrome activity may provide therapeutic benefit to individuals with type 2 diabetes.
Journal ArticleDOI
Xist RNA and the Mechanism of X Chromosome Inactivation
TL;DR: The authors are on the threshold of discovering the factors that regulate and interact with Xist to control X-inactivation, and closer to an understanding of the molecular mechanisms that underlie this complex process.
Journal ArticleDOI
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase
Inmaculada Hernández-Muñoz,Anders H. Lund,Anders H. Lund,Petra van der Stoop,Erwin Boutsma,Inhua Muijrers,E. Verhoeven,Dmitri A. Nusinow,Barbara Panning,York Marahrens,Maarten van Lohuizen,Maarten van Lohuizen +11 more
TL;DR: It is demonstrated that MACROH2A1 deposition is regulated by the CULLIN3/SPOP ligase complex and is actively involved in stable X inactivation, likely through the formation of an additional layer of epigenetic silencing.