S
Suwan Sun
Researcher at Zhejiang University
Publications - 12
Citations - 498
Suwan Sun is an academic researcher from Zhejiang University. The author has contributed to research in topics: Hepatitis B & Stem cell. The author has an hindex of 5, co-authored 12 publications receiving 226 citations.
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Journal ArticleDOI
Development of diagnostic criteria and a prognostic score for hepatitis B virus-related acute-on-chronic liver failure
Tianzhou Wu,Jiang Li,Li Shao,Jiaojiao Xin,Longyan Jiang,Qian Zhou,Dongyan Shi,Jing Jiang,Suwan Sun,Linfeng Jin,Ping Ye,Lingling Yang,Yinyun Lu,Tan Li,Jianrong Huang,Xiaowei Xu,Jiajia Chen,Shaorui Hao,Yuemei Chen,Shaojie Xin,Zhiliang Gao,Zhongping Duan,Tao Han,Yuming Wang,Jianhe Gan,Tingting Feng,Chen Pan,Yongping Chen,Hai Li,Yan Huang,Qing Xie,Shumei Lin,Lanjuan Li,Jun Li +33 more
TL;DR: Regardless of the presence of cirrhosis, patients with CHB, TB and INR ≥12 mg/dL and InR ≥1.5 should be diagnosed with ACLF, thus increasing their opportunity to receive timely intensive management.
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Quantitative evaluation of human bone mesenchymal stem cells rescuing fulminant hepatic failure in pigs
Dongyan Shi,Jianing Zhang,Qian Zhou,Jiaojiao Xin,Jing Jiang,Longyan Jiang,Tianzhou Wu,Jiang Li,Wenchao Ding,Jun Li,Suwan Sun,Jianzhou Li,Ning Zhou,Liyuan Zhang,Linfeng Jin,Shaorui Hao,Pengcheng Chen,Hongcui Cao,Mingding Li,Lanjuan Li,Xin Chen +20 more
TL;DR: An integrated model of the multifaceted interactions between stem cells and recipients is delineated, which may open a new avenue to the discovery of single molecule-based therapeutics that simulate stem cell actions.
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Development and validation of a new prognostic score for hepatitis B virus-related acute-on-chronic liver failure.
Li Jiaqi,Xi Liang,Shaoli You,Tingting Feng,Xin Zhou,Bing Zhu,Jinjin Luo,Jiaojiao Xin,Jing Jiang,Dongyan Shi,Yingyan Lu,Keke Ren,Tianzhou Wu,Lingling Yang,Li Jiang,Tan Li,Qun Cai,Suwan Sun,Beibei Guo,Xingping Zhou,Jiaxian Chen,Lulu He,Peng Li,Hui Yang,Wen Hu,Zhanglu An,Xiaojun Jin,Jin Tian,Baoju Wang,Xin Chen,Shaojie Xin,Jun Li +31 more
TL;DR: Wang et al. as discussed by the authors developed a new simplified prognostic score to accurately predict outcomes in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF).
Journal ArticleDOI
HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation
Lunzhi Yuan,Jing Jiang,Xuan Liu,Yali Zhang,Liang Zhang,Jiaojiao Xin,Kun Wu,Xiaoling Li,Jiali Cao,Guo Xueran,Dongyan Shi,Jun Li,Longyan Jiang,Suwan Sun,Tengyun Wang,Wangheng Hou,Tianying Zhang,Hua Zhu,Jun Zhang,Quan Yuan,Tong Cheng,Ningshao Xia +21 more
TL;DR: This new humanised mouse model recapitulates the liver cirrhosis induced by human HBV infection, thus providing research opportunities for understanding viral immune pathophysiology and testing antiviral therapies in vivo.
Journal ArticleDOI
PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF.
Jiang Li,Xi Liang,Jing Jiang,Lingling Yang,Jiaojiao Xin,Dongyan Shi,Yingyan Lu,Jun Li,Keke Ren,Hozeifa Mohamed Hassan,Jianing Zhang,Pengcheng Chen,Heng Yao,Li Jiaqi,Tianzhou Wu,Linfeng Jin,Ping Ye,Tan Li,Huafen Zhang,Suwan Sun,Beibei Guo,Xingping Zhou,Qun Cai,Jiaxian Chen,Xiaowei Xu,Jianrong Huang,Shaorui Hao,Jinqiu He,Shaojie Xin,Di Wang,Jonel Trebicka,Xin Chen +31 more
TL;DR: The functional synergy analysis focusing on seven bioprocesses related to the PBMC response and the top 500 differentially expressed genes (DEGs) showed that viral processes were associated with all disease stages and that immune dysregulation, as the most prominent change and disorder triggered by HBV exacerbation, drove CHB or LC to ACHD and ACLF.