S
Suyan Tian
Researcher at Jilin University
Publications - 62
Citations - 1528
Suyan Tian is an academic researcher from Jilin University. The author has contributed to research in topics: Feature selection & Cancer. The author has an hindex of 15, co-authored 57 publications receiving 1254 citations. Previous affiliations of Suyan Tian include Rockefeller University.
Papers
More filters
Journal ArticleDOI
Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
Andrea Chiricozzi,Emma Guttman-Yassky,Emma Guttman-Yassky,Mayte Suárez-Fariñas,Kristine E. Nograles,Suyan Tian,Irma Cardinale,Sergio Chimenti,James G. Krueger +8 more
TL;DR: The data predict that Psoriasis therapy with either TNF or IL-17 antagonists will produce greater modulation of the synergistic/additive gene set, which consists of the most highly expressed genes in psoriasis skin lesions.
Journal ArticleDOI
Meta-Analysis Derived (MAD) Transcriptome of Psoriasis Defines the “Core” Pathogenesis of Disease
Suyan Tian,James G. Krueger,Katherine Li,Ali Jabbari,Carrie Brodmerkel,Michelle A. Lowes,Mayte Suárez-Fariñas +6 more
TL;DR: A meta-analysis was conducted on 5 microarray data sets, including 193 LS and NL pairs, which yielded a reference list of reliable psoriasis DEGs, and represents a robust pool of candidates for further discovery of pathogenesis and treatment evaluation.
Journal ArticleDOI
Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways
David Adrian Ewald,David Adrian Ewald,David Adrian Ewald,Dana Malajian,Dana Malajian,Dana Malajian,James G. Krueger,Christopher T. Workman,Tianjiao Wang,Suyan Tian,Thomas Litman,Emma Guttman-Yassky,Emma Guttman-Yassky,Mayte Suárez-Fariñas +13 more
TL;DR: This transcriptome enriches key AD pathways more than the individual studies, and associates AD with novel pathways, such as atherosclerosis signaling (IL-37, selectin E/SELE), which reinforces the concept of AD as a systemic disease.
Journal ArticleDOI
Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris.
Andrea Chiricozzi,Andrea Chiricozzi,Mayte Suárez-Fariñas,Judilyn Fuentes-Duculan,Inna Cueto,Katherine Li,Suyan Tian,Carrie Brodmerkel,James G. Krueger +8 more
TL;DR: It has been hypothesized that inflammatory cytokines, e.g. interleukin (IL)‐17, may affect any organ or tissue having a vascular supply; thus, distant uninvolved skin could be exposed to increased circulating IL‐17.
Journal ArticleDOI
Multiple Interferon Stimulated Genes Synergize with the Zinc Finger Antiviral Protein to Mediate Anti-Alphavirus Activity
Sophiya Karki,Melody M. H. Li,John W. Schoggins,Suyan Tian,Charles M. Rice,Margaret R. MacDonald +5 more
TL;DR: The number and diversity of the identified ZAP-synergistic ISGs lead us to speculate that ZAP may play an important role in priming the cell for optimal ISG function.